GP IIIa A1/A2 genotype | ||||
---|---|---|---|---|
A1/A1 (n = 690) | A1/A2 (n = 248) | A2/A2 (n = 25) | p | |
Demographic characteristics | ||||
Male sex (%) | 80.9 | 82.7 | 64 | 0.077 |
Age (mean ± SD, years) | 64.4 ± 11.2 | 64.4 ± 11.4 | 66.2 ± 10.3 | 0.717 |
Age ≥ 65 years (%) | 53.9 | 51.6 | 64 | 0.470 |
Medical history | ||||
Hypertension (%) | 42.0 | 43.1 | 32 | 0.560 |
Diabetes mellitus (%) | 12.3 | 14.1 | 12 | 0.763 |
Hypercholesterolemia (%) | 51.6 | 50.4 | 56 | 0.512 |
Past or current smokers (%) | 50.6 | 53.2 | 40 | 0.417 |
Body Mass Index>25 (kg/m2) (%) | 63.5 | 66.1 | 52 | 0.293 |
Family history of CAD (%) | 27.8 | 29.8 | 24 | 0.755 |
Prior MI (%) | 31.2 | 30.2 | 28 | 0.915 |
Prior PCI (%) | 13.0 | 15.3 | 0 | 0.065 |
Prior CABG (%) | 10 | 8.1 | 0 | 0.204 |
Indication for PCI | ||||
Stable angina (%) | 14.3 | 18.1 | 16 | 0.752 |
Unstable angina (%) | 38.3 | 35.9 | 28 | |
Acute MI (%) | 29.3 | 27.0 | 32 | |
Post MI (%) | 11.4 | 12.1 | 16 | |
Other (%) | 4.5 | 5.2 | 8 | |
Angiographic characteristics | ||||
LVEF < 40% (%) | 15.7 | 16.1 | 8 | 0.716 |
Single vessel disease (%) | 45.4 | 42.7 | 32 | 0.576 |
Two-vessel disease (%) | 32.2 | 35.5 | 36 | |
Three-vessel disease (%) | 22.5 | 21.8 | 32 | |
Therapy at inclusion | ||||
ACE inhibitor (%) | 32.3 | 33.1 | 44 | 0.481 |
Beta-blocker (%) | 56.1 | 56.0 | 80 | 0.060 |
Statin (%) | 35.2 | 33.5 | 32 | 0.864 |