From: Plasma TF activity predicts cardiovascular mortality in patients with acute myocardial infarction
Characteristic | TF activity ≤ 24 pmol (n = 64) | TF activity > 24 pmol (n = 48) | P |
---|---|---|---|
TF Activity, (pmol) | 7.0 ± 0.90 | 54.2 ± 3.30 | <0.001 |
TF Activity + anti TFPI, (pmol) | 39.7 ± 2.25 | 65.8 ± 2.99 | <0.001 |
Demographics | Â | Â | Â |
   Median age, years | 64.5 ± 1.54 | 58.7 ± 1.95 | 0.02 |
   Male sex | 54 (84.4%) | 37 (77.1%) | 1.0 |
   Number of CV death (n) | 5 (7.8%) | 11 (22.9%) | 0.02 |
   Time to death (days) | 437.3 ± 145.72 | 218.0 ± 55.63 | 0.68 |
   Days of follow up (days) | 1460.0 ± 0.0 | 1460.0 ± 0.0 | 1.0 |
Pevious medical history | Â | Â | Â |
   Myocardial infarction | 15 (24.4%) | 8 (16.7%) | 0.005 |
   ACVB | 5 (7.8%) | 2 (4.2%) | 0.001 |
Cardiovascular risk factors | Â | Â | Â |
   Arterial hypertension | 40 (62.5%) | 34 (70.8%) | 0.17 |
   Diabetes mellitus | 14 (21.9%) | 15 (31.3%) | 0.001 |
   Hypercholesterolemia | 39 (60.9%) | 25 (52.1%) | 0.41 |
   Current smoker | 42 (65.6%) | 36 (75.0%) | 0.001 |
Biochemical markers | Â | Â | Â |
   Peak creatine kinase, U/l | 1475.0 ± 357.91 | 1897.7 ± 276.5 | 0.03 |
   C-reactive protein, mg/dl | 44.7 ± 11.22 | 26.2 ± 6.79 | 0.25 |
   NT-pro-BNP, pg/ml | 1739.4 ± 402.93 | 3946.8 ± 1442.53 | 0.28 |
Clinical data | Â | Â | Â |
   Prehospital CPR | 5 (7.8%) | 10 (20.8%) | 0.05 |
   Cardiogenic shock | 9 (14.1%) | 13 (27.1%) | 0.09 |
   Killip's class |  |  |  |
I | 47 (73.4%) | 25 (52.1%) | 0.04 |
II | 8 (12.5%) | 10 (20.8%) | 0.09 |
III | 3 (4.7%) | 6 (12.5%) | 0.60 |
IV | 6 (9.4%) | 7 (14.6%) | 0.40 |
Angiographic data | Â | Â | Â |
   Left ventricular function | 46.2 ± 1.56 | 45.3 ± 1.97 | 0.77 |
   Target vessel |  |  |  |
LAD | 27 (42.2%) | 29 (60.4%) | 0.30 |
RCA | 30 (46.9%) | 12 (25.0%) | 0.03 |
LCx | 7 (10.9%) | 7 (14.6%) | 0.57 |
   Extent of coronary artery |  |  |  |
   Disease |  |  |  |
1-vessel-disease | 18 (28.1%) | 15 (31.3%) | 0.72 |
2-vessel-disease | 18 (28.1%) | 14 (29.2%) | 0.29 |
3-vessel-disease | 28 (43.8%) | 19 (39.6%) | 0.16 |
   Medication on admission |  |  |  |
Aspirin | 64 (100%) | 48 (100%) | 1.0 |
Heparin | 12 (18.8%) | 4 (8.3%) | 0.07 |
Clopidogrel | 54 (84.4%) | 44 (91.7%) | 0.83 |
Beta-Blockers | 18 (28.1%) | 10 (20.8%) | 0.07 |
ACE-Inhibitors | 10 (15.6%) | 7 (14.6%) | 0.86 |
Statins | 12 (18.8%) | 5 (10.4%) | 0.85 |