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Table 3 The multiplicative and additive interaction between TH and PSH on VTE in stroke patients

From: The interaction effect of transfusion history and previous stroke history on the risk of venous thromboembolism in stroke patients: a prospective cohort study

Variables

VTE

No VTE

Unadjusted model

Adjusted modela

OR (95% CI)

P

OR (95% CI)

P

Multiplicative scale

 TH

90 (40.2)

134 (59.8)

3.465 (2.427, 4.946)

<0.001*

1.868 (1.224, 2.852)

0.004*

 PSH

88 (23.0)

294 (77.0)

1.432 (1.027, 1.995)

0.034*

1.436 (0.983, 2.096)

0.061

 TH * PSH

26 (63.4)

15 (36.6)

2.251 (1.033, 4.905)

0.041*

2.646 (1.080, 6.481)

0.033*

Additive scale

 Non-TH & Non-PSH

129 (13.4)

831 (86.6)

Ref

—

Ref

—

 TH & Non-PSH

64 (35.0)

119 (65.0)

3.465 (2.427, 4.946)

<0.001*

1.868 (1.224, 2.852)

0.004*

 Non-TH & PSH

62 (18.2)

279 (81.8)

1.432 (1.027, 1.995)

0.034*

1.436 (0.983, 2.096)

0.061

  TH & PSH

26 (63.4)

15 (36.6)

11.166 (5.759, 21.647)

<0.001*

7.096 (3.300, 15.260)

<0.001*

  RERI

—

—

7.270 (1.891, 17.606)

—

7.016 (1.489, 18.165)

—

  AP

—

—

0.651 (0.260, 0.793)

—

0.650 (0.204, 0.797)

—

  S

—

—

3.510 (1.568, 7.860)

—

3.529 (1.451, 8.579)

—

  1. *P<0.05 was considered statistically significant
  2. aAdjusted by age, gender, smoking, drinking, atrial fibrillation, cancer, and anticoagulants
  3. —No data