Table 4 Subgroup analysis

NIHSS score ≤ 5 points

 Multiplicative scale

  TH

26 (28.9)

64 (71.1)

3.516 (1.962, 6.299)

<0.001*

1.814 (0.891, 3.693)

0.101

  PSH

39 (15.4)

214 (84.6)

1.589 (1.008, 2.504)

0.046*

1.423 (0.835, 2.426)

0.195

  TH * PSH

7 (43.7)

9 (56.3)

1.417 (0.424, 4.734)

0.571

2.205 (0.518, 9.391)

0.285

 Additive scale

  Non-TH & Non-PSH

92 (9.0)

631 (91.0)

Ref

—

Ref

—

  TH & Non-PSH

19 (25.7)

55 (74.3)

3.516 (1.962, 6.299)

<0.001*

1.814 (0.891, 3.693)

0.101

  Non-TH & PSH

32 (13.5)

205 (86.5)

1.589 (1.008, 2.504)

0.046*

1.423 (0.835, 2.426)

0.195

  TH & PSH

7 (43.7)

9 (56.3)

7.916 (2.850, 21.987)

<0.001*

5.692 (1.663, 19.487)

0.006*

  RERI

—

—

3.811 (-1.754, 17.733)

—

3.455 (-0.887, 17.133)

—

  AP

—

—

0.481 (-0.688, 0.713)

—

0.607 (-0.773, 0.772)

—

  S

—

—

2.228 (0.609, 8.144)

—

3.793 (0.605, 23.759)

—

NIHSS score > 5 points

 Multiplicative scale

  TH

64 (47.8)

70 (52.2)

2.099 (1.310, 3.362)

0.002*

1.523 (0.888, 2.612)

0.126

  PSH

49 (38.0)

80 (62.0)

1.210 (0.729, 2.008)

0.460

1.399 (0.792, 2.470)

0.247

  TH * PSH

19 (76.0)

6 (24.0)

3.722 (1.220, 11.355)

<0.021*

3.529 (1.027, 12.122)

0.045*

 Additive scale

  Non-TH & Non-PSH

67 (25.1)

200 (74.9)

Ref

—

Ref

—

  TH & Non-PSH

45 (41.3)

64 (58.7)

2.099 (1.310, 3.362)

0.002*

1.523 (0.888, 2.612)

0.126

  Non-TH & PSH

30 (28.9)

74 (71.1)

1.210 (0.729, 2.008)

0.460

1.399 (0.792, 2.470)

0.247

  TH & PSH

19 (76.0)

6 (24.0)

9.453 (3.624, 24.654)

<0.001*

7.519 (2.607, 21.685)

<0.001*

  RERI

—

—

7.144 (1.409, 22.170)

—

5.597 (0.735, 19.593)

—

  AP

—

—

0.756 (0.236, 0.846)

—

0.744 (0.066, 0.849)

—

  S

—

—

6.457 (1.731, 24.087)

—

7.069 (1.344, 37.192)

—