| Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age ≥ 70 y | 1.818 (1.116–2.962) | 0.016* | 2.487 (1.487–4.161) | 0.001* |
Female sex | 1.038 (0.690–1.562) | 0.857 |  |  |
Stage IV disease | 2.028 (1.165–3.531) | 0.012* | 2.024 (1.131–3.623) | 0.018* |
SPE | 1.823 (1.200–2.768) | 0.005* | 1.564 (1.008–2.425) | 0.046* |
Central or lobar location | 0.808 (0.520–1.254) | 0.342 |  |  |
Central, lobar, or segmental location | 0.919 (0.599–1.411) | 0.700 |  |  |
Multiple | 1.578 (0.908–2.745) | 0.106 |  |  |
Bilateral | 1.203 (0.793–1.823) | 0.385 |  |  |
Combined with DVT | 1.184 (0.787–1.781) | 0.418 |  |  |
ECOG PS > 1 | 2.784 (1.821–4.258) | < 0.001* | 2.276 (1.429–3.626) | 0.001* |
Low BMI | 1.329 (0.539–3.278) | 0.537 |  |  |
Overweight | 0.663 (0.441–0.997) | 0.048* | 0.896 (0.590–1.359) | 0.604 |
Obesity | 0.687 (0.374–1.262) | 0.226 |  |  |
Anticoagulation therapy | 0.834 (0.515–1.353) | 0.463 |  |  |
Thrombolytic therapy | 3.762 (1.342–10.545) | 0.012* | 5.208 (1.801–15.063) | 0.002* |
Filter implantation | 0.654 (0.286–1.497) | 0.315 |  |  |
Bleeding event | 0.909 (0.468–1.765) | 0.778 |  |  |