Prognosis of incidental pulmonary embolism vs. symptomatic pulmonary embolism in cancer patients: a single-center retrospective cohort study in China

Table 8 Univariate and multivariate Cox hazard analysis of the risk factors for survival after diagnosis of SPE

	Univariate analysis		Multivariate analysis
	HR (95% CI)	P-value	HR (95% CI)	P-value
Age ≥ 70 y	2.624 (1.455–4.768)	0.001^*	3.141 (1.691–5.836)	< 0.001^*
Female sex	0.897 (0.532–1.511)	0.683
Stage IV disease	1.552 (0.801–3.009)	0.193
Central or lobar location	1.437 (0.678–3.045)	0.345
Central, lobar, or segmental location	1.482 (0.878–2.503)	0.141
Bilateral	0.682 (0.372–1.251)	0.216
Combined with DVT	1.191 (0.706–2.010)	0.513
ECOG PS > 1	2.285 (1.339–3.899)	0.002^*	2.557 (1.474–4.437)	0.001*
Low BMI	1.272 (0.505–3.205)	0.610
Overweight	0.967 (0.574–1.628)	0.899
Obesity	0.678 (0.304–1.509)	0.341
Anticoagulation therapy	0.671 (0.339–1.327)	0.251
Thrombolytic therapy	3.001 (0.913–9.868)	0.070	4.940 (1.446–16.878)	0.011^*
Filter implantation	0.924 (0.333–2.564)	0.880
Bleeding event	1.206 (0.536–2.715)	0.651

PE, pulmonary embolism; HR, hazard ratio; CI, confidence interval; DVT, deep vein thrombosis; ECOG PS, Eastern Cooperative Oncology Group performance status; BMI, body mass index; * means P < 0.05

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