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Fig. 1 | Thrombosis Journal

Fig. 1

From: A case of acquired thrombotic thrombocytopenic purpura induced by acute severe hepatitis E: successfully treated by plasma exchange and rituximab

Fig. 1

Summary of clinical course during the patient’s hospitalization. Upon admission, the patient received methylprednisolone combined with intravenous immunoglobulin pulse therapy. Methylprednisolone was tapered on day 12, day 17, and day 22, while intravenous immunoglobulin therapy was discontinued after 7 days of treatment. The patient underwent once-weekly treatment with rituximab. Due to limited plasma resources, 12 sessions of intermittent plasma exchange were performed. After receiving three platelet transfusions during the first eight days of hospitalization, the platelet counts finally increased. Platelet recovery occurred spontaneously after clinical improvement, 12 days later. The above curve illustrates the gradual return to normal of total bilirubin, alanine aminotransferase, and creatinine levels following treatment. The patient was transferred from the EICU to a general ward on day 12 and was discharged after recovery

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