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Table 1 Laboratory findings of the patient during hospitalization

From: A case of acquired thrombotic thrombocytopenic purpura induced by acute severe hepatitis E: successfully treated by plasma exchange and rituximab

 

Day1

(at admission)

Day 3

Day 7

Day 12

Day 25

Two weeks after discharge

WBC

(N: 3.5–9.5*10^9/L)

12.37

6.17

15.52

9.99

5.44

6.12

RBC

(N: 4.3–5.8 *10^9/L)

3.34

2.51

2.93

2.45

2.29

2.35

PLT

(N: 125–350 *10^9/L)

10

23

20

56

254

260

HGB

(N: 130–175 g/L)

102

75

89

81

82

113

Hypersensitivity C-reactive protein

(N: <10 mg/L)

77.4

30.2

5.1

6.9

<10

/

Procalcitonin

(N<0.5 ng/ml)

2.3

2.0

0.7

0.76

<0.5

/

TB

(N: 3.4–24 umol/L)

319.6

449.2

159.6

173.1

31.7

21.7

DB

(N:≤6.8 umol/L)

267.5

376.3

141.4

146.0

14

7.4

ALB

(N: 40–55 g/L)

19.4

30.2

30.8

38

36.8

/

CR

(N: 57–97 umol/L)

139

120

53.1

66.2

60.0

/

ALT

(N: 9–45 U/L)

484

486

129

57

45

53

AST

(N: 15–40 U/L)

1283

956

161

55

47

27

GGT

(N: 10–60 U/L)

101

54

35

110

92

92

PT

(seconds)

16.1

19.4

13.3

12.4

11.2

10.1

Others

IgG-HEV:5.9 (N<1.0),

IgM-HEV:1.3 (N<1.0)

Negative: IgG-HAV, IGM-HAV, IgG-HDV, IGM-HDV, antibody-HCB, IgM-TORCH, syphilis, ANCA, antinuclear antibodies, ammonia

ADAMTS13 activity (%): 0%,

inhibitors of ADAMTS13: positive

no abnormal cells with bone marrow puncture

    
  1. ALB, albumin; ALT, alanine aminotransferase; ANCA, antineutrophilic cytoplasmic antibody; AST, aspartate aminotransferase; CR, creatinine; DB, direct bilirubin; GGT, γ-glutamyl transpeptidase; HGB, hemoglobin; hypersensitivity C-reactive protein; IgG-HAV, immunoglobulin G for hepatitis A virus; IgG-HDV, immunoglobulin G for hepatitis D virus; IgG-HEV, immunoglobulin G for hepatitis E virus; IgM-HAV, immunoglobulin M for hepatitis A virus; IgM-HDV, immunoglobulin M for hepatitis D virus; IgM-HEV, immunoglobulin M for hepatitis E virus; IgM-TORCH, immunoglobulin M for toxoplasmosis, rubella, cytomegalovirus, herpes simplex, and HIV; PLT, platelet count; PT, prothrombin time; RBC, red blood cell; TB, total bilirubin; WBC, white blood cell