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Table 2 Laboratory values and vital signs at admission, at peak, and at the time of CTA

From: Predictors of pulmonary embolism in hospitalized patients with COVID-19

Variables

Positive chest CTA consistent with a PE (n = 66)

Negative chest CTA ruling out a PE (n = 92)

Total

P-value

 

Median (IQR)

Median (IQR)

Median (IQR)

 

Time from symptom onset to admission (days)

Admission D-dimer (ug/mL)

Admission LDH (U/L)

Admission CRP

Admission WBC

Admission Platelets

Admission total bilirubin

Admission direct bilirubin

Admission troponin

Admission BNP

Peak IL-6

Peak LDH (U/L)

Peak CRP (mg/L)

Peak D-dimer

Troponin at time of CTA

Lactate at time of CTA

PESI score at time of CTA

SBP at time of CTA

DBP at time of CTA

SpO2 at time of CTA

Heart rate at time of CTA

7 (2–14)

6.87 (2.10–20)

476.5 (353.75-6)

105.65 (68.8-199.5)

10.2 (6.5-14.78)

272.5 (195.25–349)

0.8 (0.6–1.2)

0.4 (0.3–0.5)

0.015 (0.01–0.097)

27.08 (10.3-95.48)

74.6 (27.23–130.5)

555 (377.5-696.25)

226.5 (124.7-302.3)

9.26 (2.60–20)

0.02 (0.01–0.1)

1.7 (1.3–2.9)

125.5 (113.3-140.5)

126 (111–141)

75 (66–82)

96 (94–98)

104 (86–114)

4 (2–7)

1.59 (0.79–3.4)

415.5 (308-591.8)

105 (42.01–192.9)

7.45 (5.9–10.4)

199.5 (158.8-261.3)

0.5 (0.4–0.9)

0.3 (0.2–0.5)

0.01(0.00-0.03)

25.8 (10.0-63.8)

61.15 (28.03–218.6)

558 (401.5–813)

196.2 (103.1-272.6)

3.8 (1.47–8.92)

0.01 (0.01–0.04)

1.6(1.2-2.0)

117.5 (100.8-133.5)

126( 114-136.5)

76 (70–83)

95 (93-97.3)

99.5 (86–110)

5 (2–10)

2.32 (1.14–10.7)

440 (319.5-619.5)

105.45 (55.4-198.4)

8.1 (6.1–12.3)

216 (170-316.3)

0.7 (0.4-1)

0.3 (0.2–0.5)

0.013 (0.01–0.05)

25.9 (10.0-71.2)

72.75 (26.675-174)

558 (386-789.5)

209 (113.04–281.4)

4.7 (1.71–17.5)

0.02 (0.01–0.06)

1.7 (1.2–2.3)

122 (105–136)

126 (112.8–138)

75 (68–83)

95 (93–98)

101 (86–113)

0.05

< 0.0001

0.29

0.22

0.005

0.001

0.003

0.021

0.01

0.34

0.67

1.00

0.17

0.0008

0.26

0.26

0.006

0.76

0.15

0.37

0.45

  1. Note – Continuous variables are presented as means and standard deviations for normally distributed data or as medians and interquartile ranges for nonparametric data. Differences in distributions of characteristics of those with and those without pulmonary embolism (PE) were analyzed using Student t test or Mann-Whitney U test. Bold indicates statistical significance (p < 0.05). CTA = computed tomography pulmonary angiography; LDH = lactate dehydrogenase; CRP = c-reactive protein; WBC = white blood cell; BNP = B-type natriuretic peptide; IL-6 = interleukin-6; PESI = pulmonary embolism severity index; SBP = systolic blood pressure; DBP = diastolic blood pressure