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Table 1 The characteristics of the included studies in the meta-analysis

From: Aspirin and clopidogrel resistance; a neglected gap in stroke and cardiovascular practice in Iran: a systematic review and meta-analysis

The first author

Investigated drug

Publication Date

Type of study

Study location

Types of diseases

Test

Number of the patients

Age

(year)

Sex

Female (%)

Prevalence of resistance

(%)

Hypertension (%)

Hyperlipidemia (%)

Diabetes (%)

Ref.

Sadeghi, M

Aspirin

2012

Retrospective study

Isfahan (center)

ischemic heart disease

Thromboxane B2 level in urine (ELISA)

170

60.42 ± 8.43

79 (46.5)

75.3%

58.8%

47.1%

25.3%

25

Kojuri, J

Aspirin

2010

Crossover

Shiraz

(center)

percutaneous coronary

angioplasty

light transmission aggregometry

106

56.07 ± 10.13

66 (62.26)

30.2%

54.7%

84.9%

12.2%

24

Eskandarian, R

Aspirin

2012

Cross-sectional

Semnan

(north eastern)

coronary artery diseases

urinary 11-dehydro-thromboxane B.

124

61.8 ± 9.7

50 (40.3)

49.2%

33.8%

NR

28.2%

23

Aghajania, HM

clopidogrel

2018

Cross-sectional

Tehran

(center)

angioplasty

light

transmission aggregometry (LTA)

105

60.30 ± 12.2

64 (61%)

24.76%

65.71%

NR

20.95%

21

Aghajani, HM

clopidogrel

2013

Before-and-after

Tehran

(center)

undergoing angioplasty

light transmission aggregometry (LTA)

31

59 ± 13

12 (38.7)

13%

54.8%

NR

19.4%

22

  1. Ref: reference, NR: not reported