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Table 1 Patient characteristics

From: Net reclassification index in comparison of prognostic value of disseminated intravascular coagulation diagnostic criteria by Japanese Society on Thrombosis and Hemostasis and International Society on Thrombosis and Haemostasis: a multicenter prospective cohort study

 

Survivor

Non-survivor

p-value

 

n = 191

n = 31

Demographics

   

Age (years)

68 (56 to 78)

71 (60 to 79)

0.34

Male

115 (60.2)

19 (61.3)

0.91

Underlying disease types

  

0.25

Hematopoietic disorders

71 (64.5)

11 (35.5)

 

Infectious diseases

77 (71.0)

9 (29.0)

 

The others

43 (64.5)

11 (35.5)

 

Laboratory tests

   

Platelets (× 103/µL)

69 (40 to 164)

39 (14 to 128)

0.006

FDP (µg/mL)

22.05 (11.5 to 44.7)

22.72 (13.7 to 116.7)

0.19

D-dimer (µg/mL)

14.6 (8.5 to 28.0)

13.0 (8.5 to 70.0)

0.68

PT-INR

1.2 (1.05 to 1.41)

1.4 (1.2 to 1.54)

0.003

Fibrinogen (mg/dL)

270 (186 to 422)

212 (128 to 282)

0.013

AT (%)

85.8 (67.8 to 101.9)

74.8 (59.3 to 88.5)

0.013

TAT* (ng/mL)

10.85 (6.09 to 30.7)

32.18 (11 to 145.73)

< 0.001

SF (µg/mL)

43.4 (18.1 to 103)

52.9 (17.5 to 215)

0.23

F1 + 2† (pmol/L)

748 (416 to 1201)

849.5 (324 to1201)

0.99

Liver failure

NA

1 (3.2)

NA

Anti-DIC agents

   

rhTM

81 (42.6)

21 (67.7)

0.009

Antithrombin

39 (20.5)

11 (35.5)

0.065

  1. FDP, fibrinogen/fibrin degradation products; PT-INR, prothrombin time-international normalized ratio; fibrinogen, antithrombin; AT, thrombin-antithrombin complex; TAT, soluble fibrin; SF, prothrombin fragment F1 + 2, F1 + 2; rhTM, recombinant human soluble thrombomodulin; NA, not applicable
  2. * One patient had a missing TAT value
  3. † There were 17 patients with missing F1 + 2