Table 2 Pool analysis of association between inflammatory markers and VTE
Inflammatory markers | Involved studies | Num. of cases (VTE vs. Health control) | MD, 95%CI |
|---|---|---|---|
Part I | Â | Â | Â |
WBC, ×109/L | Olson, 2014; Tsai, 2002 | 427 vs. 46,617 | −0.05,−0.23—0.14 |
CRP, ug/ml | Tsai, 2002 | 89 vs. 307 | −0.40,−1.23—0.43 |
hs-CRP*, ug/ml | Olson, 2014 | 268 vs. 27,539 | 0.63, 0.21—1.05 |
CRP > 3ug/ml | Olson, 2014; Zacho, 2010; Folsom, 2018 | 459/16,108 vs. 671/29,817# | 1.39, 1.23—1.57ξ |
Part II | Â | Â | Â |
WBC, ×109/L | Rattazzi, 2013; Yang, 2015; Artoni, 2018 | 902 vs. 636 | 0.32,−0.22—0.85 |
Neutrophil, ×109/L | Rattazzi, 2013; Artoni, 2018 | 826 vs. 539 | 0.20,−0.62—1.02 |
Lymphocyte, ×109/L | Rattazzi, 2013; Yang, 2015; Artoni, 2018 | 902 vs. 636 | −0.01,−0.07—0.06 |
Monocyte, ×109/L | Rattazzi, 2013 | 240 vs. 240 | 0.03, 0.00—0.05 |
PLR | Artoni, 2018 | 586 vs. 299 | −4.74,−11.02—1.54 |
NLR | Artoni, 2018 | 586 vs. 299 | −0.10,−0.23—0.03 |
hs-CRP*, ug/ml | Rattazzi, 2013; Vormittag, 2005; Matos, 2011; Luxembourg, 2009 | 674 vs. 672 | 0.85, 0.61—1.08 |
CRP, ug/ml | Artoni, 2018 | 586 vs. 299 | 0.66, 0.20—1.13 |
IL−6*, pg/ml | Poredos, 2011; Matos, 2011 | 168 vs. 174 | 0.47, 0.25—0.70 |
Part III | Â | Â | Â |
WBC, ×109/L | Farah, 2019; Bakirci, 2015; Reiter, 2003; Zakai, 2013; Ming, 2018; KAMIŞLI, 2012; Akboga, 2017; Zakai, 2004; Tekeşin, 2019 | 1016 vs. 1245 | 1.43, 0.88—1.98 |
Neutrophil, ×109/L | Farah, 2019; Ming, 2018; Kurtipek, 2015; KAMIŞLI, 2012; Akboga, 2017; Tekeşin, 2019 | 609 vs. 480 | 1.79, 1.02—2.56 |
Lymphocyte, ×109/L | Farah, 2019; Ming, 2018; Kurtipek, 2015; KAMIŞLI, 2012; Akboga, 2017; Tekeşin, 2019 | 609 vs. 480 | −0.23,−0.35—−0.12 |
Monocyte, ×109/L | Ming, 2018; Tekeşin, 2019 | 151 vs. 145 | 0.17, 0.14—0.21 |
PLR | Farah, 2019; Ming, 2018; Kurtipek, 2015; Akboga, 2017; Tekeşin, 2019 | 574 vs. 453 | 33.11, 24.45—41.78 |
NLR | Farah, 2019; Bakirci, 2015; Ming, 2018; Kurtipek, 2015; KAMIŞLI, 2012; Akboga, 2017; Wang 2018; Tekeşin, 2019 | 781 vs. 555 | 1.34, 0.95—1.73 |
hs-CRP, ug/ml | Bakirci, 2015; Zhou, 2015; Wang 2018; Tekeşin, 2019 | 276 vs. 197 | 3.72, 1.45—5.99 |
CRP, ug/ml | Reiter, 2003; Ramacciotti, 2011; Lowe, 2000 | 148 vs. 279 | 1.05,−0.79—2.88 |
IL−6, pg/ml | Wang 2018 | 95 vs. 41 | 5.99, 4.52—7.46 |