Table 2 Clinical outcomes of patients stratified by baseline symptoms

Recurrence or aggravation of symptomatic VTE

1.8 (0.7–4.0)

3.1 (1.5–5.5)

0.60 (0.22–1.62)

0.31

1.7 (0.6–3.8)

3.1 (1.9–4.8)

0.56 (0.23–1.40)

0.21

Recurrence or aggravation of symptomatic PE

0.9 (0.2–2.7)

2.5 (1.1–4.5)

0.37 (0.10–1.35)

0.12

0.3 (0.0–1.6)

1.1 (0.4–2.2)

0.26 (0.03–2.15)

0.18

Recurrence or aggravation of symptomatic DVT

1.2 (0.3–3.2)

0.8 (0.2–2.4)

1.49 (0.33–6.67)

0.60

1.4 (0.5–3.4)

2.2 (1.2–3.6)

0.68 (0.24–1.88)

0.45

Acute coronary syndrome

0

0.3 (0.0–1.5)

-

0.35

0.3 (0.0–1.6)

0.2 (0.0–0.8)

1.90 (0.12–30.36)

0.64

Ischemic stroke

1.2 (0.3–3.1)

1.1 (0.3–2.8)

1.11 (0.28–4.45)

0.88

0

0

-

-

Death from any cause

5.2 (3.0–8.3)

4.6 (2.7–7.4)

1.11 (0.57–2.18)

0.76

6.5 (4.1–9.8)

5.6 (4.0–7.7)

1.17 (0.69–1.96)

0.56

Death related to VTE

0.6 (0.1–2.2)

0.5 (0.1–2.0)

1.11 (0.16–7.89)

0.92

0.3 (0.0–1.6)

0.5 (0.1–1.4)

0.62 (0.06–5.94)

0.67

Death related to CVD

0.9 (0.2–2.7)

0.5 (0.1–2.0)

1.67 (0.28–9.99)

0.57

0.3 (0.0–1.6)

1.1 (0.4–2.2)

0.27 (0.03–2.19)

0.19

Major bleeding

1.9 (0.5–4.9)

2.7 (1.1–5.7)

0.68 (0.20–2.33)

0.58

5.2 (1.9–11.4)

3.0 (1.5–5.2)

1.47 (0.54–3.97)

0.45

Minor bleeding

3.4 (1.4–7.0)

9.5 (6.0–14.3)

0.36 (0.15–0.83)

0.004

12.4 (6.8–20.8)

9.1 (6.3–12.6)

1.03 (0.55–1.92)

0.94

Fatal bleeding

0

0

-

-

0

0.5 (0.1–1.3)

-

0.21

Clinically relevant events

7.8 (5.1–11.6)

9.5 (6.5–13.3)

0.83 (0.49–1.39)

0.48

9.9 (6.8–13.9)

9.4 (7.2–12.1)

1.05 (0.69–1.61)

0.82