Development and validation of a new risk assessment model for immunomodulatory drug-associated venous thrombosis among Chinese patients with multiple myeloma

Table 2 Derivation and validation of the new RAM score using multivariate Cox regression analysis

Variable	Derivation cohort		Validation cohort		Point value
Variable	HR	P value	HR	P value	Point value
Dexamethasone	5.511	0.002	17.304	0.005	3
Diabetes	2.412	0.016	3.037	0.006	1
Erythropoietin	6.241	< 0.001	3.122	0.018	3
History of VTE or family history of thrombosis	5.001	< 0.001	1.819	0.233	3
ECOG > 2	2.288	0.015	2.397	0.011	1
Risk stratification
High/low	6.08	< 0.001	6.23	< 0.001	High if > 4
C index	0.64	95% CI: 0.60–0.69	0.62	95% CI: 0.59–0.66

ISSN: 1477-9560