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Fig. 2 | Thrombosis Journal

Fig. 2

From: Damage-associated molecular patterns and fibrinolysis perturbation are associated with lethal outcomes in traumatic injury

Fig. 2

The elevation of serum histone H3 levels is associated with the subsequent elevation of plasminogen activator inhibitor-1. a Relationships between plasminogen activator inhibitor-1 (PAI-1) levels and platelet (PLT) counts, thrombin-antithrombin complex (TAT), plasmin-alpha2-plasmin inhibitor complex (PIC), histone H3, high mobility group box 1 protein (HMGB1), and injury severity score (ISS) levels in patients with severe trauma are shown. The intensities of the correlations are color-coded according to Spearman’s rho values, with deep purple colors indicating strong correlations. b Correlation between PAI-1 levels at 6 h and circulating histone H3 levels at admission (n = 29) and at 6 h (n = 29) are shown

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Thrombosis Journal

ISSN: 1477-9560

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