Fig. 5
From: GDF15 affects venous thrombosis by promoting EndMT through smad2/p-smad2 pathway
WB results, mouse serum GDF15 and blood clot section staining after drug treatment. (A) WB results showed that on the basis of cytokine stimulation, CMK significantly inhibited the maturation of GDF15. (B) Elisa was used to detect the serum GDF15 level of mice. There was no significant increase of GDF15 in the CMK inhibitor group after modeling, and the scale was 200 μm (100×). *, # p < 0.05, * is compared with CON group, and # is compared with VTE group. (C) Masson and Sirius red staining showed that the content of thrombe fibers in the CMK treated group of mice was reduced (Masson fibers were dyed blue, Sirius red fibre dyed red), the scale was 200 μm (100×)