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Table 1 Frequencies of PC R189W and K193del in patients with history of VTE and in healthy controls in the Chinese cohort

From: Evaluation of prothrombotic risk of two PROC hotspot mutations (Arg189Trp and Lys193del) in Chinese population: a retrospective study

Mutation

Genotype

Control group n (%)

VTE group n (%)

PC R189W

Wide-type (R/R)

Heterozygote (R/W)

407 (99.3)

3 (0.7)

463 (94.5)

27 (5.5)

 
 

Homozygote (W/W)

0 (0)

0 (0)

 

PC K193del

Wide-type (K/K)

Heterozygote (K/del)

403 (98.3)

7 (1.7)

447 (91.2)

41 (8.4)

 
 

Homozygote (del/del)

0 (0)

2 (0.4)

 
  1. PC, protein C; VTE, venous thromboembolism