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Table 2 Interventions and patient outcomes stratified by PERT presence and PERT consultation

From: Reduced mortality associated with pulmonary embolism response team consultation for intermediate and high-risk pulmonary embolism: a retrospective cohort study

 

PERT PRESENT

 

PERT CONSULTED

Interventions and Patient Outcomes

Pre-PERT:

n = 317 patients1

Post-PERT:

n = 369 patients1

p-value2

PERT NOT

CONSULTED: n = 168 patients1

PERT

CONSULTED: n = 201 patients1

p-value2

Systemic Anticoagulant

308 (96.6%)

355 (96.7%)

0.9

156 (94.0%)

199 (99.0%)

0.007*

Systemic Anticoagulation

Medication

  

1.0

  

0.02*

 Apixaban

4 (1.3%)

7 (2.0%)

 

3 (1.9%)

4 (2.0%) 0

 

 Argatraban

0 (0%)

1 (0.3%)

 

1 (0.6%)

(0%)

 

 Dalteparin

16 (5.2%)

3 (0.8%)

 

1 (0.6%)

2 (1.0%)

 

 Edoxaban

1 (0.3%)

0 (0%)

 

0 (0%)

0 (0%)

 

 Enoxaparin

54 (18%)

106 (30%)

 

38 (24%)

68 (34%)

 

 Other

0 (0%)

1 (0.3%)

 

0 (0%)

1 (0.5%)

 

 Rivaroxaban

11 (3.6%)

10 (2.8%)

 

4 (2.5%)

6 (3.0%)

 

 Unfiltered Heparin

217 (71%)

228 (64%)

 

110 (70%)

118 (59%)

 

 Warfarin

2 (0.7%)

1 (0.3%)

 

1 (0.6%)

0 (0%)

 

Time to Therapeutic AC (Hours)

8 (6, 20)

8 (6, 22)

0.6

8 (6, 23)

8 (6, 15)

0.3

Number of Procedures

66 (20.8%)

42 (11.4%)

0.01*

16 (9.5%)

26 (12.9%)

0.4

Procedural Intervention

      

 Catheter-Directed Lysis

15 (4.7%)

2 (0.5%)

 < 0.001*

1 (0.6%)

1 (0.5%)

 > 0.9

 IVC Filter

42 (13.2)

24 (6.5%) 1

0.003*

13 (7.8%)

11 (5.5%) 1

0.4

 Surgical Intervention

4 (1.3%)

(0.3%)

0.2

0 (0.0%)

(0.5%)

 > 0.9

 Thromboaspiration

5 (1.6%)

15 (4.1%)

0.050

2 (1.2%)

13 (6.5%)

0.015*

Systemic Thrombolysis

20 (6.3%)

19 (5.2%)

0.5

4 (2.4%)

15 (7.5%)

0.030*

Hospital Length of Stay

(days)

6 (2, 11)

6 (3, 12)

0.12

9 (4, 18)

4 (2, 8)

 < 0.001*

ICU Length of Stay (days)

0 (0, 4)

0 (0, 4)

0.6

2 (0, 7)

0 (0, 2)

 < 0.001*

30-Day Mortality

  

0.78

  

0.0024*

 Alive at 30 Days

276 (87.0%)

321 (87.0%)

 

132 (80%)

189 (94%)

 

 Dead at 30 Days

37 (12.0%)

43 (12.0%)

 

33 (20%)

10 (5.0%)

 

 Unknown

3 (1.9%)

3 (0.8%)

 

1 (0.6%)

2 (1.0%)

 

Goals of Care Precluded PERT Consult

– –

12 (7.1%) N/A

  1. 1Median (IQR), n (%)
  2. 2Wilcoxon rank sum test, Pearson’s Chi-squared test, Fisher’s exact test