Table 2 Different types of technologies for hemostasis point-of-care testing.
From: Point-of-Care Testing of Hemostasis in Cardiac Surgery
DEVICE (MANUFACTURER) | MAIN TESTS | PRINCIPLE | TYPE OF DETECTION |
|---|---|---|---|
Hemochron series (ITC, USA) | ACT, PT, aPTT RxDX system | Magnet position | Optical detection of change in magnet position in a slowly rotating reagent-filled tube |
Hemochron Junior II and Signature (ITC, USA) | ACT+ and LR, PT, aPTT | Fluid oscillation | Optical detection of slowing of oscillatory motion in a test channel |
ACT II, Hepcon HMS (Medtronic Hemotec, USA) | HRACT, LRACT, HR-HCT, HMS, HEMOSTATUS PT, aPTT | Plunger motion | Optical detection of change in the fall rate of a plunger assembly that is raised and lowered |
RapidpointCoag (Bayer, USA) | PT, PT-ONE, aPTT, HMT | Particle motion | Optical detection of slowing of motion of paramagnetic iron oxide particles in pulsating magnetic field |
I-STAT (ABBOTT, USA) | Celite-ACT | Electrochemical conversion | Amperometrical detection of an electroactive product from the conversion of thrombin substrate |
CoaguChek Plus and Pro (Roche Diagnostics, USA) | PT, aPTT, ACT | Pattern recognition | Optical detection of change in laser interference pattern from slowing cell motion |
ACTALYKE (Array Medical, USA) | ACT, MAX-ACT, PT, aPTT | Electromechanical recognition | Two point electromechanical soft-clot detection |
TegR Analyzer (Hemoscope, USA) | Thromboelastogram | Cup oscillation | Mechanical or electrical detection in changes of oscillation of cup and pin together |
ROTEGR Analyzer (Pentapharm, BMBH) | Thromboelastogram | Shaft rotation | Optomechanical detection of loss of motion of shaft |
SONOCLOT (Sienco, USA) | Sonoclot Signature | Impedance on vibrating probe | Impedance detection of changes in viscoelastic properties of celite-activated blood sample |
PFA-100 (Dade Behring, USA) | ADP/CT, EPI/CT | Pressure | Detection of change in pressure across porous aperture when platelet aggregates occlude openings |