The transmembrane receptor molecule CD31 is known to have immunomodulatory functions, suggesting a possible neuroprotective effect in the context of acute ischemic stroke by restricting an over-activation of secondary immunological processes. This study examines the density of CD31+ cells in mechanically extracted thrombi of stroke patients with the aim to test whether the occurrence of CD31+ cells was associated with a beneficial clinical outcome in those patients.

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March is blood clot awareness month and the theme for this year is “Know More, Share More”. So to aid in the sharing of knowledge on blood clots and strokes we invited associate editor of Thrombosis Journal, Bob Siegerink, to tell us about updating Virchow’s triad for thrombotic diseases and the importance of communication between stroke and thrombosis researchers.

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Recognized on 13 October, World Thrombosis Day seeks to increase global awareness of thrombosis. In appreciation of this day, we asked representatives from Thrombosis Journal, the Asian-Pacific Society of Thrombosis and Haemostasis (APSTH) and the International Society on Thrombosis and Haemostasis (ISTH) to share their knowledge of the condition.

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State of the Art 2016: Research and Review from the 9th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis

​​​​​​The 9th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis was held from 6-9 October 2016 in Taipei, Taiwan.

As the official journal of the APSTH, Thrombosis Journal has published a supplement of state of the art review and research articles in conjunction with the congress.

Inflammation and its role in thrombosis

In recent years it has become increasingly clear that the immune system and coagulation pathways interact and influence one another. Inflammation-induced thrombosis is considered a feature of several autoimmune diseases and thus such findings have important consequences for the treatment and management of such diseases.

 "Open access is a critical element in dissemination of knowledge and research data throughout the world. In the field of thrombosis and haemostasis many developments are relevant, not only for the developed world, but also for those in underdeveloped nations where access to journals may be limited. The strength of Thrombosis Journal is that is can be accessed by everyone, everywhere. I strongly encourage scientists to submit their valuable data (clinical and basic research) to Thrombosis Journal, where we provide a platform for the full range of thrombosis and haemostasis related topics (also including case reports and special issue contributions)."

 Hugo ten Cate, Editor-in-Chief, Thrombosis Journal