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  1. Recently, heparin-induced thrombocytopenia (HIT) after vaccination with the vaccines manufactured by AstraZeneca and Pfizer–BioNTech has been published in the New England Journal of Medicine. These reports state ...

    Authors: Kenji Yamamoto

    Citation: Thrombosis Journal 2021 19:67

    Content type: Letter to the Editor

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  2. This is a review article on heparin-induced thrombocytopenia, an adverse effect of heparin therapy, and vaccine-induced immune thrombotic thrombocytopenia, occurring in some patients administered certain coron...

    Authors: Payel Datta, Fuming Zhang, Jonathan S. Dordick and Robert J. Linhardt

    Citation: Thrombosis Journal 2021 19:66

    Content type: Review

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  3. Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but fatal complication of the Coronavirus Disease 2019 vaccine. The many reports of VITT have mostly been in the Caucasian population. Here, ...

    Authors: Archrob Khuhapinant, Tarinee Rungjirajittranon, Bundarika Suwanawiboon, Yingyong Chinthammitr and Theera Ruchutrakool

    Citation: Thrombosis Journal 2021 19:65

    Content type: Case report

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  4. Protein S deficiency (PSD) is an autosomal dominant hereditary disease. In 1984, familial PSD was reported to be prone to recurrent thrombosis. Follow-up studies have shown that heterozygous protein S (PROS1) mut...

    Authors: Yan-ping Zhang, Bin Lin, Yuan-yuan Ji, Ya-nan Hu, Xin-fu Lin, Yi Tang, Jian-hui Zhang, Shao-jie Wu, Sen-lin Cai, Yan-feng Zhou, Ting Chen, Zhu-ting Fang and Jie-wei Luo

    Citation: Thrombosis Journal 2021 19:64

    Content type: Research

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  5. DOAC detection is challenging in emergency situations. Here, we demonstrated recently, that modified thromboelastometric tests can reliably detect and differentiate dabigatran and rivaroxaban. However, whether...

    Authors: Simon T. Schäfer, Anne-Christine Otto, Alice-Christin Acevedo, Klaus Görlinger, Steffen Massberg, Tobias Kammerer and Philipp Groene

    Citation: Thrombosis Journal 2021 19:63

    Content type: Research

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  6. Intermittent pneumatic compression (IPC) is commonly used to prevent deep vein thrombosis (DVT) during hospitalization in patients with acute stroke. However, if DVT exists at admission, IPC of the legs with D...

    Authors: Takahisa Mori, Kazuhiro Yoshioka and Yuhei Tanno

    Citation: Thrombosis Journal 2021 19:62

    Content type: Research

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  7. Immune thrombocytopenia (ITP) is an autoimmune disease characterized as a low platelet count resulting from immune-mediated platelet destruction. Dimethyl fumarate (DMF) is widely applied for the treatment of ...

    Authors: Huan Tong, Yangyang Ding, Xiang Gui, Zengtian Sun, Guozhang Wang, Sixuan Zhang, Zhengqing Xu, Xiamin Wang, Xiaoqi Xu, Wen Ju, Yue Li, Zhenyu Li, Lingyu Zeng, Kailin Xu and Jianlin Qiao

    Citation: Thrombosis Journal 2021 19:61

    Content type: Research

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  8. Thrombin generation (TG) assessed by Calibrated Automated Thrombogram (CAT-I) reflects the overall capacity of plasma to generate thrombin, thus evaluating the balance between the anti- and procoagulant proces...

    Authors: P. L. A. Giesen, A. J. W. Gulpen, R. van Oerle, H. ten Cate, M. Nagy and H. M. H. Spronk

    Citation: Thrombosis Journal 2021 19:60

    Content type: Research

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  9. Thrombosis plays an important role in the Coronavrus Disease 2019 (COVID-19) infection-related complications such as acute respiratory distress syndrome and myocardial infarction. Multiple factors such as oxyg...

    Authors: Mahin Behzadi Fard, Samaneh Behzadi Fard, Shahin Ramazi, Amir Atashi and Zahra Eslamifar

    Citation: Thrombosis Journal 2021 19:59

    Content type: Review

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  10. Previous studies have shown conflicting results regarding the influence of cardiovascular risk-factors on venous thromboembolism. This study aimed to determine if these risk-factors, i.e. physical activity, sm...

    Authors: C. J. MacDonald, A. L. Madika, M. Lajous, M. Canonico, A. Fournier and M. C. Boutron-Ruault

    Citation: Thrombosis Journal 2021 19:58

    Content type: Research

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  11. The coronavirus disease (COVID-19) pandemic has led to an unprecedented worldwide burden of disease. However, little is known of the longer-term implications and consequences of COVID-19. One of these may be a...

    Authors: Rajiv Advani, Torbjørn Austveg Strømsnes, Espen Stjernstrøm and Sebastian T. Lugg

    Citation: Thrombosis Journal 2021 19:57

    Content type: Case report

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  12. Coronavirus disease 2019 (COVID-19) pneumonitis associated with severe respiratory failure is associated with high mortality. The pathogenesis of COVID-19 is associated with microembolism or microvascular endo...

    Authors: Fumihiro Ogawa, Yasufumi Oi, Kento Nakajima, Reo Matsumura, Tomoki Nakagawa, Takao Miyagawa, Kazuya Sakai, Ryo Saji, Hayato Taniguchi, Kohei Takahashi, Takeru Abe, Masayuki Iwashita, Mototsugu Nishii and Ichiro Takeuchi

    Citation: Thrombosis Journal 2021 19:55

    Content type: Research

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  13. We review the evidence for tranexamic acid (TXA) for the treatment and prevention of bleeding caused by surgery, trauma and bleeding disorders. We highlight therapeutic areas where evidence is lacking and disc...

    Authors: Anna Ockerman, Thomas Vanassche, Melisa Garip, Christophe Vandenbriele, Matthias M Engelen, Jeroen Martens, Constantinus Politis, Reinhilde Jacobs and Peter Verhamme

    Citation: Thrombosis Journal 2021 19:54

    Content type: Review

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  14. Data are limited on patient background characteristics associated with catheter ablation (CA)-related bleeding events in Japanese patients with non-valvular atrial fibrillation receiving uninterrupted periproc...

    Authors: Ichitaro Abe, Naohiko Takahashi, Yasushi Mukai, Tetsuya Kimura, Keita Yamaguchi, Atsushi Takita, Hideki Origasa and Ken Okumura

    Citation: Thrombosis Journal 2021 19:53

    Content type: Research

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  15. Phlebitis, inflammation of tunica intima of venous wall, occurred in 13–56% of hospitalized patients. It is characterized by pain, erythema, swelling, palpable venous cord, and pussy discharge at catheter site...

    Authors: Mulugeta Lulie, Abilo Tadesse, Tewodros Tsegaye, Tesfaye Yesuf and Mezgebu Silamsaw

    Citation: Thrombosis Journal 2021 19:48

    Content type: Research

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  16. Statins are a potential treatment for venous thromboembolism (VTE) prophylaxis complementary to conventional anticoagulants without associated bleeding complications. This study aimed to compare pro-thrombotic...

    Authors: Mohammadreza Bordbar, Renée de Mutsert, Melike Cevval, Frits R. Rosendaal, J. Wouter Jukema and Willem M. Lijfering

    Citation: Thrombosis Journal 2021 19:45

    Content type: Research

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  17. Although the rate of childhood acute lymphoblastic leukemia (ALL) is increasing in Africa, there is a dearth of information on the disease and the dynamics of hemostatic parameters with therapy.

    Authors: William Osei-OWusu, David Ofosu Ntiamoah, Gordon Asare Akuffo, Selina Mintaah, Michael Owusu, Benedict Sackey, Lilian Antwi-Boateng, Ganiwu Abdul, Max Annani-Akollor, Eddie-Williams Owiredu, Alexander Yaw Debrah and Otchere Addai-Mensah

    Citation: Thrombosis Journal 2021 19:44

    Content type: Research

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  18. Coronavirus disease 2019 (COVID-19) associated coagulopathy (CAC) leads to thromboembolic events in a high number of critically ill COVID-19 patients. However, specific diagnostic or therapeutic algorithms for...

    Authors: Johannes Herrmann, Quirin Notz, Tobias Schlesinger, Jan Stumpner, Markus Kredel, Magdalena Sitter, Benedikt Schmid, Peter Kranke, Harald Schulze, Patrick Meybohm and Christopher Lotz

    Citation: Thrombosis Journal 2021 19:39

    Content type: Research

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  19. Deep vein thrombosis (DVT) is common in critically ill patients with Coronavirus disease 2019 (COVID-19) and may cause fatal pulmonary embolism (PE) prior to diagnosis due to subtle clinical symptoms. The aim ...

    Authors: Sarah Galien, Michael Hultström, Miklós Lipcsey, Karl Stattin, Robert Frithiof and Jacob Rosén

    Citation: Thrombosis Journal 2021 19:38

    Content type: Research

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  20. There is a need for clinical outcome data of cerebral venous thrombosis (CVT) in cancer patients. We examined the recanalization, thrombosis recurrence and major bleeding during CVT treatment in a cancer exclu...

    Authors: Nadia I Abelhad, Wei Qiao, Naveen Garg and Cristhiam M. Rojas-Hernandez

    Citation: Thrombosis Journal 2021 19:37

    Content type: Research

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    The Correction to this article has been published in Thrombosis Journal 2021 19:49

  21. Coagulopathy is the major cause of mortality and morbidity throughout the world. Globally, about 26–45% of healthy people have a history of bleeding symptoms, which may be a result of thrombocytopenia, factor ...

    Authors: Melak Aynalem, Elias Shiferaw, Yemataw Gelaw and Bamlaku Enawgaw

    Citation: Thrombosis Journal 2021 19:36

    Content type: Research

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  22. The incidence of pulmonary thromboembolism is high in SARS-CoV-2 patients admitted to the Intensive Care. Elevated biomarkers of coagulation (fibrinogen and D-dimer) and inflammation (c-reactive protein (CRP) ...

    Authors: Mark M. G. Mulder, LIoyd Brandts, Renée A. G. Brüggemann, Marcel Koelmann, Alexander S. Streng, Renske H. Olie, Hester A. Gietema, Henri M. H. Spronk, Iwan C. C. van der Horst, Jan-Willem E. M. Sels, Joachim E. Wildberger, Sander M. J. van Kuijk, Ronny M. Schnabel, Hugo ten Cate, Yvonne M. C. Henskens and Bas C. T. van Bussel

    Citation: Thrombosis Journal 2021 19:35

    Content type: Research

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  23. Enoxaparin is an anticoagulant that falls in the class of medications called low molecular weight heparins (LMWHs), and is used to prevent or treat patients with deep vein thrombosis (DVT) and pulmonary emboli...

    Authors: Tao Xiang and Ming Cheng

    Citation: Thrombosis Journal 2021 19:34

    Content type: Case report

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  24. Dual antiplatelet therapy can reduce coronary thrombosis and improve the prognosis in patients with acute coronary syndrome (ACS). However, there was limited prognostic information about fibrinolytic dysregula...

    Authors: Huaibin Wan, Xin Fan, Zhihao Wu, Zhenbang Lie, Daqiang Li and Shaohui Su

    Citation: Thrombosis Journal 2021 19:33

    Content type: Research

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  25. COVID-19 can induce thrombotic disease both in the venous and arterial circulations, as a result of inflammation, platelet activation, endothelial dysfunction, and stasis. Although several studies have describ...

    Authors: Ehsan Aghaei Moghadam, Shima Mahmoudi, Alieh Safari Sharari, Mehrnoush Afsharipour, Mojtaba Gorji, Amene Navaeian, Azin Ghamari and Setareh Mamishi

    Citation: Thrombosis Journal 2021 19:31

    Content type: Case report

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  26. Associations between D-dimer and outcomes of patients with acute coronary syndromes (ACS) remain controversial. This study aimed to investigate the prognostic value of D-dimer in ACS patients treated by percut...

    Authors: Runzhen Chen, Chen Liu, Peng Zhou, Yu Tan, Zhaoxue Sheng, Jiannan Li, Jinying Zhou, Yi Chen, Li Song, Hanjun Zhao and Hongbing Yan

    Citation: Thrombosis Journal 2021 19:30

    Content type: Research

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  27. Platelet count can be altered in various diseases and treatments and measuring it may provide better insight into the expected outcome. So far, quantification of platelet count is done within laboratory condit...

    Authors: Magdolna Nagy, Sepanta Fazaeli, René van Oerle, Hugo ten Cate, Marcel Schemmann, John Sherry, Gillian Kelleher and Henri M. H. Spronk

    Citation: Thrombosis Journal 2021 19:29

    Content type: Research

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  28. For patients taking warfarin and undergoing pacemaker or implantable cardioverter-defibrillator surgery, clinical evidence and guidelines support continuation of warfarin therapy, as opposed to interruption of...

    Authors: Andrew Kei-Yan Ng, Pauline Yeung Ng, Eva Wai-Ying Tam, Chung-Wah Siu and Katherine Fan

    Citation: Thrombosis Journal 2021 19:28

    Content type: Research

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  29. Sphingomyelin (SM) is an essential component of biological lipid rafts, and it plays an indispensable role in maintaining plasma membrane stability and in mediating signal transduction. The ultimate biosynthes...

    Authors: Yifan Guo, Lin Chang, Ge Zhang, Zhanyan Gao, Hao Lin, Yuting Zhang, Liang Hu, She Chen, Bing Fan, Si Zhang and Ruyi Xue

    Citation: Thrombosis Journal 2021 19:27

    Content type: Research

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  30. Coronavirus disease (COVID-19) pneumonitis associated with severe respiratory failure has a high mortality rate. Based on recent reports, the most severely ill patients present with coagulopathy, and dissemina...

    Authors: Fumihiro Ogawa, Yasufumi Oi, Kento Nakajima, Reo Matsumura, Tomoki Nakagawa, Takao Miyagawa, Takeru Abe and Ichiro Takeuchi

    Citation: Thrombosis Journal 2021 19:26

    Content type: Case report

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  31. The purpose of this study is to elucidate the association between peripherally inserted central venous catheter (PICC) in upper extremities and lower extremity deep venous thrombosis (LEDVT) by observing the c...

    Authors: Wanli Liu, Lianxiang He, Wenjing Zeng, Liqing Yue, Jie Wei, Shuangshuang Zeng, Xiang Wang and Zhicheng Gong

    Citation: Thrombosis Journal 2021 19:24

    Content type: Research

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  32. Patients on dialysis are at higher risk of major bleeding and recurrent thrombosis creating acute venous thromboembolism (VTE) treatment challenges. DOACs represent an interesting option but there are concerns...

    Authors: Guillaume Roberge and Philip Stephen Wells

    Citation: Thrombosis Journal 2021 19:23

    Content type: Case report

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  33. Little is known about the difference in the severity of cardioembolic (CE) stroke between patients with paroxysmal atrial fibrillation (PAF) and persistent/permanent AF (PerAF). We assessed stroke severity in ...

    Authors: Joji Hagii, Norifumi Metoki, Shin Saito, Hiroshi Shiroto, Satoko Sasaki, Koki Takahashi, Hiroyasu Hitomi, Yoshiko Baba, Natsumi Yamada, Satoshi Seino, Takaatsu Kamada, Takamitsu Uchizawa, Taigen Nakamura, Minoru Yasujima and Hirofumi Tomita

    Citation: Thrombosis Journal 2021 19:22

    Content type: Research

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  34. Antiphospholipid syndrome (APS) is a non-inflammatory autoimmune disorder induced by antiphospholipid antibodies, which occurs exceedingly rarely in pediatric population and even more rarely reported in HIV po...

    Authors: Rong-Jing Dong, Su-Yun Lei, Jun Li, Xin-Ping Yang, Yu-Ye Li and Yun-Gui Zhang

    Citation: Thrombosis Journal 2021 19:20

    Content type: Case report

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  35. Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS) is characterized by bleeding and thrombosis in patients with autoimmune diseases or infections. Paediatric LAHPS exhibits various degrees of bleeding, r...

    Authors: Atsushi Sakamoto, Masao Ogura, Atsushi Hattori, Kinji Tada, Reiko Horikawa, Hisaya Nakadate, Kimikazu Matsumoto, Keiji Nogami, Masahiro Ieko and Akira Ishiguro

    Citation: Thrombosis Journal 2021 19:19

    Content type: Case report

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  36. Determination of anticoagulant therapy is of pronounced interest in emergency situations. However, routine tests do not provide sufficient insight. This study was performed to investigate the impact of anticoa...

    Authors: Philipp Groene, Daniela Wagner, Tobias Kammerer, Lars Kellert, Andreas Giebl, Steffen Massberg and Simon Thomas Schäfer

    Citation: Thrombosis Journal 2021 19:18

    Content type: Research

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  • Thrombosis Journal is the official journal of the Asian-Pacific Society on Thrombosis and Hemostasis.

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