Table 3 Variables of ex vivo and in vivo thrombin generation in subgroups of patients with stable CAD
From: Markers of hypercoagulability in CAD patients. Effects of single aspirin and clopidogrel treatment
ETP | F1+2 | D-dimer | |
|---|---|---|---|
(nM·min) | (pmol/L) | (ng/ml) | |
Male (n = 771) | 1439 (1240, 1599) | 192 (146, 257) | 381 (264, 595) |
Female (n = 210) | 1416 (1231, 1620) | 251 (183, 356) | 477 (338, 660) |
p-value | 0.745 | <0.001 (<0.001*) | <0.001 (0.033*) |
Smoking - (n = 779) | 1423 (1225, 1590) | 205 (152, 276) | 394 (279, 613) |
Smoking + (n = 202) | 1466 (1291, 1633) | 204 (153, 281) | 419 (285, 609) |
p-value | 0.018 (0.014*) | 0.789 | 0.605 |
MI - (n = 552) | 1425 (1226, 1597) | 202 (152, 277) | 397 (273, 602) |
MI + (n = 429) | 1441 (1241, 1610) | 206 (154, 277) | 403 (285, 626) |
p-value | 0.325 | 0.567 | 0.428 |
T2DM - (n = 786) | 1439 (1219, 1602) | 207 (155, 278) | 399 (278, 607) |
T2DM + (n = 195) | 1427 (1279, 1597) | 192 (145, 263) | 391 (283, 616) |
p-value | 0.671 | 0.079 | 0.667 |
MetS - (n = 739) | 1420 (1208, 1581) | 207 (157, 287) | 399 (277, 614) |
MetS + (n = 241) | 1504 (1301, 1654) | 187 (143, 251) | 400 (282, 603) |
p-value | <0.001 (0.283*) | 0.002 (0.927*) | 0.972 |
HT - (n = 436) | 1430 (1224, 1603) | 195 (148, 266) | 377 (256, 583) |
HT + (n = 545) | 1440 (1246, 1601) | 210 (156, 287) | 419 (298, 625) |
p-value | 0.835 | 0.053 (0.532*) | 0.01 (0.358*) |
RAS inhib - (n = 491) | 1440 (1210, 1619) | 195 (145, 260) | 383 (262, 561) |
RAS inhib + (n = 483) | 1436 (1245, 1590) | 209 (159, 286) | 419 (292, 658) |
p-value | 0.579 | 0.005 (0.013†) | 0.001 (0.060†) |
β-blockers - (n = 236) | 1466 (1229, 1615) | 200 (148, 258) | 390 (267, 551) |
β-blockers + (n = 737) | 1433 (1239, 1600) | 206 (153, 278) | 401 (284, 626) |
p-value | 0.540 | 0.335 | 0.090 |