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Table 2 Incidence of MACCE and bleeding events in patients with an indication for OAC receiving TT after PCI-S

From: Triple antithrombotic therapy in patients with atrial fibrillation undergoing coronary artery stenting: hovering among bleeding risk, thromboembolic events, and stent thrombosis

Author MACCE (%) Bleeding (%)
  All cause mortality MI Ichemic Stroke Overall Major Overall
Orford JL et al.[9] NR NR NR 0 3.1 9.2
Mattichak SJ et al.[10] 3 29 0 NR NR 21¥
Khurram Z et al.[11] 0.9 0 0 NR 6.6 21.5
Porter A et al.[12] NR NR NR NR 1 11
Lip GYH & Karpha M[13] NR NR NR NR 0 0*
Karjalainen PP et al.[14] 8.7 10 3.2 25.1 8.2 NR
DeEugenio D et al.[15] 1 NR NR NR 13.5 NR
Rubboli A et al.[16] 0 0 0 0 14.3 20
Nguyen MC et al.[17] 5.1 3.3 0.7 NR 5.9§ NR
Rogacka RCA et al.[18] 3.9 1.6 NR 23.6 4.7 7.1
Ruiz-Nodar JM et al.[19]^ 17.8 6.5 1.7 26.5 14.9 27.5
M.-Fernandez S et al.[20] 5.9° NR NR 25.5 27.4 NR
Sarafoff N et al.[21] 10.7 3.7 1.1 14.1 1.4 9.1
Maegdefessel L et al.[22] 7.1 0 0 NR 0 NR
Rossini R et al.[23] 2 NR 1 5.8 2.9 10.8
Valencia J et al.[24] NR NR NR NR NR NR
Gao F et al.[25] 4.4 2.9 0.7 8.8 2.9 11.8
Sambola A et al.[26] 6.8 NR 0.3 7.9 4.3 15.5
Gilard M et al.[27] 8 5 0.8 NR 5.6 18.4
Hälg C et al.[28] NR NR NR NR 6.1 NR
Halbfass P et al.[29] NR NR NR 21 8 NR
Helft G et al.[30] 0 6 0 6 0 2
Olson KL et al.[31] 14.8° 0 NR 15.4 14.3 NR
Baber J et al.[32] 5.9 1.8 NR 11.8 1.1 4.6§
Persson J et al.[33] 3.6 9 NR NR 2.3 4.1
Uchidab Y et al.[34] 8 0 4 22 18 38
Guasch E et al.[35] NR NR NR NR 0 12.1
Jang SW et al.[36] 3.6 3.6 1.2 26.2 10.7 13.1
  1. MACCE= major adverse cardiovascular and cerebrovascular events ; OAC= oral anticoagulation; TT= triple therapy;
  2. PCI-S= percutaneous coronary intervention with stent implantation; NR= not reported.
  3. ¥ transfusions * requiring hospitalization § in-hospital events ^ data are related to anticoagulated patients, 88% of whom treated with TT ° cardiovascular-related death.