From: New oral anticoagulants: are coagulation units still required?
Study drug: endpoint, bleeding
Daily dose
Dabigatran[8]
50 mg × 2
150 mg × 2
300 mg
225 mg × 2
Clinically important %
2.3
4.1
4.9
5.1
Rivaroxaban[9, 10]
5 mg
10 mg
20 mg
30 mg
Major after surgery %
2.2
4.5
5.4
Edoxaban[11]
30 mg × 2
60
60 mg × 2
Major + clinically relevant %
3.0
7.8
3.8
10.6
