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Table 2 Efficacy and bleeding in patients treated with oral anticoagulant + clopidogrel (double therapy) or oral anticoagulant + clopidogrel + aspirin (triple therapy) (data modified from[19])

From: New oral anticoagulants: are coagulation units still required?

Secondary and safety endpoints at 1 year Double therapeutic % Triple therapeutic % n NNT
Total efficacy 11.1 17.6 0.025 15
Deaths (all causes) 2.5 6.5 0.027 25
Myocardial infarction 3.2 4.6 0.328 71
Stroke 1.1 2.5 0.128 71
Stent thrombosis 1.4 3.2 0.125 56
Any bleeding event 19.4 44.4 <0.001 4.0
  1. NNT: Number need to treat.