Table 2 Efficacy and bleeding in patients treated with oral anticoagulant + clopidogrel (double therapy) or oral anticoagulant + clopidogrel + aspirin (triple therapy) (data modified from[19])
From: New oral anticoagulants: are coagulation units still required?
Secondary and safety endpoints at 1 year | Double therapeutic % | Triple therapeutic % | n | NNT |
|---|---|---|---|---|
Total efficacy | 11.1 | 17.6 | 0.025 | 15 |
Deaths (all causes) | 2.5 | 6.5 | 0.027 | 25 |
Myocardial infarction | 3.2 | 4.6 | 0.328 | 71 |
Stroke | 1.1 | 2.5 | 0.128 | 71 |
Stent thrombosis | 1.4 | 3.2 | 0.125 | 56 |
Any bleeding event | 19.4 | 44.4 | <0.001 | 4.0 |