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Table 2 Data of homocysteine metabolism parameters of study group and control subjects.

From: Homocysteine, MTHFR C677T gene polymorphism, folic acid and vitamin B 12 in patients with retinal vein occlusion

Test (unit of measurement)

RVO subjects (69)

GC subjects (50)

P

Hcy (nmol/ml)

14.7 ± 9.9

10.2 ± 8

0.02

PL-Hcy (nmol/ml)

42.7 ± 23.7

30.4 ± 13.3

<0.01

Δ-tHcy (nmol/ml)

27.8 ± 21.5

21.0 ± 16.0

<0.01

Serum folic acid (ng/ml)

6.27 ± 3.8

7.22 ± 3.5

Ns

Serum B12 vit. (pg/ml)

403.3 ± 202.0

601.6 ± 145.4

Ns

MTHFR C677T heterozigosity (%)

46,7

56,25

Ns

MTHFR C677T homozigosity (%)

29,3

4,17

<0.01

  1. Hcy: homocysteine
  2. PL-Hcy, post load homocysteine
  3. Δ-tHcy: total homocysteine increase
  4. MTHFR: methylene tetra hydrofolate reductase
  5. RVO: retinal vein occlusion
  6. CG: control group
  7. Ns: not significant