Table 1 Precision analysis of each parameter of thrombin generation curve given by Thrombogram-Thrombinoscope assessed in fresh PRP in the presence of increasing TF concentrations or with out any TF addition. CV: coefficient of variation.
Recombiplastin final dilution in plasma and approximate TF concentration | Lag-time | Tmax | Cmax | ETP | ||||
|---|---|---|---|---|---|---|---|---|
intra-assay CV | inter-assay CV | intra-assay CV | inter-assay CV | intra-assay CV | inter-assay CV | intra-assay CV | inter-assay CV | |
0 (0 pM) | 7% | 14% | 5% | 12% | 5% | 7% | 4% | 6% |
1/2000 (3 pM) | 4% | 4% | 4% | 6% | 6% | 9% | 4% | 11% |
1/1000 (6 pM) | 4% | 4% | 3% | 5% | 6% | 8% | 3% | 10% |
1/500 (12 pM) | 5% | 6% | 4% | 6% | 6% | 8% | 4% | 5% |
1/200 (30 pM) | 6% | 9% | 5% | 9% | 3% | 5% | 4% | 8% |