Skip to main content

Advertisement

Table 2 Prevalence of genetic defects among Caucasians [15]

From: Hereditary thrombophilia

  Incident VTE (%) Recurrent VTE (%) Normal population Relative thrombotic risk
Activated Protein C resistance (Factor V Leiden) 20 40–50 3–7 3–7 heterozygotes 50–100 homozygotes
Prothrombin G20210A mutation 3–8 15–20 1–3 2–8 heterozygotes
Antithrombin deficiency 1–2 2–5 0.02–0.04 5
Protein C deficiency 2–5 5–10 0.2–0.5 6–10
Protein S deficiency 1–3 5–10 0.1–1 2