Table 2 Prevalence of genetic defects among Caucasians [15]
From: Hereditary thrombophilia
| Â | Incident VTE (%) | Recurrent VTE (%) | Normal population | Relative thrombotic risk |
|---|---|---|---|---|
Activated Protein C resistance (Factor V Leiden) | 20 | 40–50 | 3–7 | 3–7 heterozygotes 50–100 homozygotes |
Prothrombin G20210A mutation | 3–8 | 15–20 | 1–3 | 2–8 heterozygotes |
Antithrombin deficiency | 1–2 | 2–5 | 0.02–0.04 | 5 |
Protein C deficiency | 2–5 | 5–10 | 0.2–0.5 | 6–10 |
Protein S deficiency | 1–3 | 5–10 | 0.1–1 | 2 |