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Table 4 RVVT-based Lupus Ratio before and after the addition of polybrene and heparin. RVVT-based Lupus Ratios were determined in LA-positive and LA-negative patient plasmas before and after the addition of polybrene 3.96 μg/ml and/or heparin 0.5 U/ml. RVVT-based Lupus Ratio <1.11 = negative result.

From: Detection and quantification of lupus anticoagulants in plasma from heparin treated patients, using addition of polybrene

 

RVVT-based Lupus Ratio median (range)

 
 

LA-positive patients n = 12

LA-negative patients n = 13

Lupus Ratio

1.33 (1.14 to 1.63)

0.99 (0.88 to 1.06)

Lupus ratio with polybrene

1.36 (1.20 to 1.69)

1.03 (0.92 to 1.11)

% change

2.33 (-1.52 to +10.16)

2.94 (-1.02 to +9.57)

Lupus ratio with heparin and polybrene

1.32 (1.16 to 1.52)

1.01 (0.87 to 1.08)

% change

-2.51 (-9.40 to +6.78)

1.09 (-3.03 to +5.21)