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Table 1 Influence of particulate matter exposed rat lung on the endogenous thrombin potential (ETP) in thrombin generation.

From: A new method to determine tissue specific tissue factor thrombomodulin activities: endotoxin and particulate air pollution induced disbalance

Treatment

ETP at 4 hrs

(nM.min)

ETP at 48 hrs

(nM.min)

0.3 mg RTD/kg

231 ± 105

103 ± 77

1 mg RTD/kg

264 ± 102

154 ± 128

3 mg RTD/kg

324 ± 102

288 ± 119

10 mg RTD/kg

390 ± 148*

1164 ± 199#

10 mg EHC-93/kg

264 ± 64*

1449 ± 32#

0.9% NaCl

175 ± 61

116 ± 60

  1. RTD: Road tunnel dust environmental air pollution, EHC-93: urban dust environmental air pollution. * denotes significant difference compared to 0.9% NaCl treatment at 4 hrs. # denotes significant difference compared to 0.9% NaCl treatment at 48 hrs.