Figure 5
From: Human activated protein C variants in a rat model of arterial thrombosis
Ex vivo anticoagulant response in rat plasma. The coagulation times were measured with either the APTT reagent Platelin LS (A) or with the tissue-factor reagent Simplastin Excel (B). Baseline values were obtained at -2 minutes. The randomized substances were injected at -1 minutes, followed by clamp release at 0 minutes (n = 10 in all treatment groups, n = 20 in the control group). The medians are shown.