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Table 1 Genotype distributions of VKORC1 1173 C>T, CYP2C9*2 and CYP2C9*3 polymorphisms in the investigated patients (MAF = minor allele frequency).

From: Warfarin dose and INR related to genotypes of CYP2C9 and VKORC1 in patients with myocardial infarction

Genotype Total material N = 212 Warfarin N = 58 ASA N = 72 Warfarin + ASA N = 47
  Number of patients (genotype frequency in %) MAF (%) Number of patients (genotype frequency in %) MAF (%) Number of patients (genotype frequency in %) MAF (%) Number of Patients (genotype Frequency in %) MAF (%)
VKORC1         
1173 C>T   36.6   40.5   36.1   33.0
   CC 85 (40.1)   20 (34.5)   30 (41.7)   23 (48.9)  
   CT 99 (46.7)   29 (50.0)   32 (44.4)   17 (36.2)  
   TT 28 (13.2)   9 (15.5)   10 (13.9)   7 (14.9)  
CYP2C9         
   *1/*1 147 (69.3)   40 (69.0)   48 (66.7)   33 (70.2)  
   *1/*2 38 (17.9) 11.3 12 (20.7) 11.2 10 (13.9) 7.6 8 (17.0) 17.0
   *2/*2 4 (1.9)   -   -   4 (8.5)  
   *1/*3 20 (9.4) 5.7 5 (8.6) 5.2 12 (16.7) 10.4 2 (4.3) 2.1
   *3/*3 1 (0.5)   -   1 (1.4)   -  
   *2/*3 2 (0.9)   1 (1.7)   1 (1.4)   -