Polymorphism | Allele | na | Freq. | Genotype | nb | Freq. |
---|---|---|---|---|---|---|
Thrombotic risk variants in general population (N = 469) | ||||||
Factor V Leiden | ||||||
1691G>A | G | 892 | 0.951 | GG | 423 | 0.902 |
A | 46 | 0.049 | GA | 46 | 0.098 | |
AA | 0 | 0.000 | ||||
Prothrombin | ||||||
20210G>A | G | 921 | 0.982 | GG | 453 | 0.966 |
A | 17 | 0.018 | GA | 15 | 0.032 | |
AA | 1 | 0.002 | ||||
MTHFR | ||||||
677C>T | C | 547 | 0.583 | CC | 162 | 0.345 |
T | 391 | 0.417 | CT | 223 | 0.475 | |
TT | 84 | 0.179 | ||||
1298A>C | A | 705 | 0.752 | AA | 264 | 0.563 |
C | 233 | 0.248 | AC | 177 | 0.377 | |
CC | 28 | 0.060 | ||||
Warfarin pharmacogenetic variants in individuals with predisposition to thrombosis (N = 58) | ||||||
CYP2C9 | ||||||
430C>Tc | C | 98 | 0.845 | *1/*1 | 35 | 0.603 |
T | 18 | 0.155 | *1/*2 | 9 | 0.155 | |
*2/*2 | 2 | 0.035 | ||||
1075A>Cc | A | 0.897 | *1/*3 | 7 | 0.121 | |
C | 12 | 0.103 | *2/*3 | 5 | 0.086 | |
*3/*3 | 0 | 0.000 | ||||
VKORC1 | ||||||
1639G>A | G | 66 | 0.569 | GG | 20 | 0.345 |
A | 50 | 0.431 | GA | 26 | 0.448 | |
AA | 12 | 0.207 |