Figure 2
From: Dual targeting of CCR2 and CX3CR1 in an arterial injury model of vascular inflammation
CME stained cross section of mouse femoral artery (a) with no injury and (b)14 days after endoluminal injury in wildtype mouse, (c) wildtype mouse fed CCR2 antagonist, and (d) CX3CR1 KO mouse fed CCR2 antagonist . IEL is marked by arrows. Note the lack of a visible intima with the IEL defining the vessel lumen in the uninjured artery (a). The neointima overlies the IEL in the injured animals (b-d).