Table 4 Frequencies of TF and TFPI polymorphisms in women with CHD according to T2DM or not
Genotype | T2DM+ (46) n(%) | T2DM- (172) n(%) | p |
|---|---|---|---|
TF -1812 | |||
CC | 24 (52.2) | 57 (33.1) | 0.018 |
CT | 17 (37.0) | 83 (48.3) | |
TT | 5 (10.9) | 32 (18.6) | |
Allele T frequency | 0.294 | 0.428 | |
TF -603 | |||
AA | 24 (52.2) | 57 (33.1) | 0.018 |
AG | 17 (37.0) | 83 (48.3) | |
GG | 5 (10.9) | 32 (18.6) | |
Allele G frequency | 0.294 | 0.428 | |
TF 5466 | |||
AA | 36 (78.3) | 140 (81.4) | >0.2 |
AG | 9 (19.6) | 31 (18.0) | |
GG | 1 (2.2) | 1 (0.6) | |
Allele G frequency | 0.120 | 0.096 | |
TFPI -399 | |||
CC | 37 (80.4) | 119 (69.2) | 0.133 |
CT | 9 (19.6) | 49 (28.5) | |
TT | 0 | 4 (2.3) | |
Allele T frequency | 0.098 | 0.166 | |
TFPI -287 | |||
TT | 34 (73.9) | 125 (72.7) | >0.2 |
TC | 9 (19.6) | 42 (24.4) | |
CC | 3 (6.5) | 5 (2.9) | |
Allele C frequency | 0.163 | 0.151 | |
TFPI -33 | |||
TT | 24 (52.2) | 89 (51.7) | >0.2 |
TC | 21 (45.7) | 69 (40.1) | |
CC | 1 (2.2) | 14 (8.1) | |
Allele C frequency | 0.251 | 0.282 |