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Table 4 Frequencies of TF and TFPI polymorphisms in women with CHD according to T2DM or not

From: Gender differences of polymorphisms in the TF and TFPI genes, as related to phenotypes in patients with coronary heart disease and type-2 diabetes

Genotype T2DM+ (46) n(%) T2DM- (172) n(%) p
TF -1812    
CC 24 (52.2) 57 (33.1) 0.018
CT 17 (37.0) 83 (48.3)  
TT 5 (10.9) 32 (18.6)  
Allele T frequency 0.294 0.428  
TF -603    
AA 24 (52.2) 57 (33.1) 0.018
AG 17 (37.0) 83 (48.3)  
GG 5 (10.9) 32 (18.6)  
Allele G frequency 0.294 0.428  
TF 5466    
AA 36 (78.3) 140 (81.4) >0.2
AG 9 (19.6) 31 (18.0)  
GG 1 (2.2) 1 (0.6)  
Allele G frequency 0.120 0.096  
TFPI -399    
CC 37 (80.4) 119 (69.2) 0.133
CT 9 (19.6) 49 (28.5)  
TT 0 4 (2.3)  
Allele T frequency 0.098 0.166  
TFPI -287    
TT 34 (73.9) 125 (72.7) >0.2
TC 9 (19.6) 42 (24.4)  
CC 3 (6.5) 5 (2.9)  
Allele C frequency 0.163 0.151  
TFPI -33    
TT 24 (52.2) 89 (51.7) >0.2
TC 21 (45.7) 69 (40.1)  
CC 1 (2.2) 14 (8.1)  
Allele C frequency 0.251 0.282  
  1. Calculations are performed with comparison for the heterozygous and homozygous pooled, versus the wild type.
  2. p-values refer to differences between diabetes versus non-diabetes.