Figure 3
From: Assays of different aspects of haemostasis – what do they measure?
Contribution of platelets and fibrinolysis to the decrease in ROTEM® or FOR curves. In normal individuals, the decrease in ROTEM curve amplitude (left) or FOR G’ (right) occur even in the presence of tranexamic acid (Cyklokapron®) in doses capable of preventing fibrinolysis induced by added t-PA (light grey curve). On the contrary, the decrease was platelet-dependent, as it was totally absent in platelet free plasma (PFP, dark grey curve).