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Table 2 Abnormalities in coagulation, anticoagulation and fibrinolytic system in IBD

From: Thrombosis in inflammatory bowel diseases: what’s the link?

Coagulation factors

Fibrinolytic factors

Plasma coagulation inhibotors

↑ Fibrinogen

↓ tPA

↓ AT III

↑ Prothrombin

↑ PAI-1

↓ TFPI

↑ Factors: Va, VIIa, VIIIa, Xa,XIa, XIIa

↑ TAFI

Conflicting data about PS and PC

↑ Prothrombin factors 1+2

  

↑ Thrombin-antithrombin III complex (TAT)

  

↑ Fibrinopeptide A and B

  

↑ Microparticles

  

↓ Factor XIII