Fig. 1
From: Inhibition of thrombin generation in human plasma by phospholipid transfer protein
Inhibition of thrombin generation by rPLTP. Normal pooled human plasma was mixed with various concentrations of rPLTP, and thrombin generation was initiated by adding the following procoagulant stimuli with 30 mM CaCl2: a sulfatides (20 μM); b factor XIa (0.13 nM final) plus corn trypsin inhibitor; or c tissue factor. Concentrations of rPLTP used with different procoagulant stimuli were: a 0, 5, 10, 20, 40 and 80 μg/ml corresponding to the lines from left to right; b 0, 5 (top two lines which overlap each other), 10 and 40 μg/ml corresponding to the lines from top to bottom; and c 0, 5 and 10 (three lines which overlap each other), and 40 μg/ml of rPLTP (bottom line)