Inhibition of thrombin generation in human plasma by phospholipid transfer protein

Thrombosis Journal

Table 1 Quartile-based Odds Ratio (OR) for association of low PLTP activity (≤25th percentile)

	PLTP activity		PLTP mass
Model and adjustments	OR (95%CI)	p	OR (95%CI)	p
I. No adjustment	2.2 (0.78-5.9)	0.15	1.3 (0.46-3.8)	0.59
II. BMI + HDL	2.7 (0.91- 7.8)	0.07	0.53 (0.14-2.1)	0.55
III. II + FV Leiden + prothrombin nt20210A	3.5 (1.1-12)	0.04	0.49 (0.1-1.8)	0.37
IV II + LDL-C + TG	5.2 (1.5-19)	0.01	0.84 (0.23-3.0)	0.79
V. III+ LDL-C + TG	12 (2.4-56)	0.002	0.62 (0.15-2.6)	0.52

The odds ratios (OR) for unprovoked VTE with low levels (≤25th percentile) of PLTP activity and PLTP mass are shown. Models were adjusted by variables as indicated, including BMI, HDL-C, LDL-C and TG which were used as continuous values and factor V Leiden and prothrombin nt20210A

ISSN: 1477-9560