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Table 2 Patient characteristics related to first intake of dabigatran

From: Safety and efficacy of switching from low molecular weight heparin to dabigatran in patients undergoing elective total hip or knee replacement surgery

  THR TKR Total
Treated 81 87 168
Time from last enoxaparin to first dose dabigatran (hours)    
N 79 82 161
Median (Q1, Q3) 24.0 (24.0, 24.0) 24.0 (24.0, 24.0) 24.0 (24.0, 24.0)
Minimum 9 4 4
Maximum 48 48 48
Time from last enoxaparin to first oral dose class (n [%])    
0 – <14 hours 2 (2.5) 6 (7.3) 8 (5.0)
14 – <22 hours 4 (5.1) 2 (2.4) 6 (3.7)
22 – <26 hours 65 (82.3) 59 (72.0) 124 (77.0)
≥26 hours 8 (10.1) 15 (18.3) 23 (14.3)
Missing 2 (2.5) 5 (5.7) 7 (4.2)
Time to first oral dose after end of surgery (hours)    
N 79 83 162
Median (Q1, Q3) 35.0 (31.3, 101.7) 33.6 (29.0, 99.3) 34.3 (29.8, 99.5)
Time to first oral dose after end of surgery class    
Prior to end of surgery 0 0 0
0 – <1 hours 1 (1.2) 0 1 (0.6)
1 – <4 hours 4 (4.9) 5 (5.7) 9 (5.4)
4 – <8 hours 0 3 (3.4) 3 (1.8)
8 – <24 hours 0 0 0
≥24 hours 74 (91.4) 75 (86.2) 149 (88.7)
Missing 2 (2.5) 4 (4.6) 6 (3.6)
Relationship of first dabigatran dose to date of discharge (n [%])    
1 or more days before discharge 68 (84.0) 67 (77.0) 135 (80.4)
On day of, or 1 day after, discharge 10 (12.3) 10 (11.5) 20 (11.9)
Missing 3 (3.7) 10 (11.5) 13 (7.7)
  1. Q Quartile