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Table 1 Baseline characteristics of the total populating and according to the presence of low or high RPR

From: vWF/ADAMTS13 is associated with on-aspirin residual platelet reactivity and clinical outcome in patients with stable coronary artery disease

  Total population Low RPR (n = 741) High RPR (n = 258) p-value§
Age (years)a 62.4 (36–81) 62.6 (36–81) 61.7 (41–80) 0.154
Sex, female, n (%) 218 (21.8) 159 (21.5) 58 (22.5) 0.731
Caucasian, n (%) 968 (96.8) 724 (97.7) 243 (94.2) 0.006
Cardiovascular risk factors, n (%)
 Current smoking 203 (20.3) 136 (18.4) 67 (26.0) 0.009
 Hypertension 556 (55.7) 433 (58.4) 123 (47.9) 0.003
 Diabetes mellitus 200 (20.0) 148 (20.0) 52 (20.2) 0.950
 Previous CVDd 635 (63.6) 462 (62.3) 172 (66.9) 0.189
  - Previous myocardial infarction 436 (43.7) 314 (42.4) 121 (47.1) 0.195
Systolic blood pressure (mmHg)b 140 ± 19 141 ± 19 136 ± 19 < 0.001
Diastolic blood pressure (mmHg)b 82 ± 10 82 ± 10 81 ± 9 0.040
Body mass index (kg/m2)b 27.4 ± 3.7 27.5 ± 3.8 27.2 ± 3.5 0.237
Blood tests
 Total cholesterol (mmol/L)b 4.55 ± 0.98 4.55 ± 0.99 4.53 ± 0.96 0.793
 LDL cholesterol (mmol/L)b 2.53 ± 0.83 2.53 ± 0.83 2.53 ± 0.83 0.998
 HDL cholesterol (mmol/L)b 1.33 ± 0.41 1.34 ± 0.42 1.31 ± 0.37 0.277
 Triglycerides (mmol/L)c 1.31 (0.93, 1.84) 1.29 (0.91, 1.84) 1.35 (0.97, 1.85) 0.144
 Residual platelet reactivity, n (%) 258 (25.8)    
 TxB2 (ng/mL)a 2.7 (0–21) 2.6 (0–21) 3.0 (0–15) 0.102
Medication, n (%)
 Statins 982 (98.3) 727 (98.2) 254 (98.4) 0.825
 B-blockers 755 (75.8) 561 (76.1) 193 (74.8) 0.672
 Calcium channel blockers 255 (25.6) 196 (26.5) 59 (23.0) 0.272
 ACE-inhibitors 263 (26.5) 200 (27.1) 63 (24.7) 0.455
 ARB 239 (24.0) 187 (25.3) 52 (20.4) 0.111
  1. CVD cardiovascular disease, MI myocardial infarction, PCI percutaneous coronary intervention, CABG coronary artery bypass graft, TxB 2 thromboxane B2, ACE angiotensin-converting enzyme, ARB angiotensin II receptor blockers
  2. § p-values refer to differences between the groups with high or low RPR
  3. amean (range) bmean ± SD cmedian (25th, 75th percentiles) dPrevious MI, PCI, CABG, non-haemorrhagic stroke
  4. Significant p-values are highlighted with boldface