Table 1 Baseline characteristics of the total populating and according to the presence of low or high RPR
Total population | Low RPR (n = 741) | High RPR (n = 258) | p-value§ | |
|---|---|---|---|---|
Age (years)a | 62.4 (36–81) | 62.6 (36–81) | 61.7 (41–80) | 0.154 |
Sex, female, n (%) | 218 (21.8) | 159 (21.5) | 58 (22.5) | 0.731 |
Caucasian, n (%) | 968 (96.8) | 724 (97.7) | 243 (94.2) | 0.006 |
Cardiovascular risk factors, n (%) | ||||
Current smoking | 203 (20.3) | 136 (18.4) | 67 (26.0) | 0.009 |
Hypertension | 556 (55.7) | 433 (58.4) | 123 (47.9) | 0.003 |
Diabetes mellitus | 200 (20.0) | 148 (20.0) | 52 (20.2) | 0.950 |
Previous CVDd | 635 (63.6) | 462 (62.3) | 172 (66.9) | 0.189 |
- Previous myocardial infarction | 436 (43.7) | 314 (42.4) | 121 (47.1) | 0.195 |
Systolic blood pressure (mmHg)b | 140 ± 19 | 141 ± 19 | 136 ± 19 | < 0.001 |
Diastolic blood pressure (mmHg)b | 82 ± 10 | 82 ± 10 | 81 ± 9 | 0.040 |
Body mass index (kg/m2)b | 27.4 ± 3.7 | 27.5 ± 3.8 | 27.2 ± 3.5 | 0.237 |
Blood tests | ||||
Total cholesterol (mmol/L)b | 4.55 ± 0.98 | 4.55 ± 0.99 | 4.53 ± 0.96 | 0.793 |
LDL cholesterol (mmol/L)b | 2.53 ± 0.83 | 2.53 ± 0.83 | 2.53 ± 0.83 | 0.998 |
HDL cholesterol (mmol/L)b | 1.33 ± 0.41 | 1.34 ± 0.42 | 1.31 ± 0.37 | 0.277 |
Triglycerides (mmol/L)c | 1.31 (0.93, 1.84) | 1.29 (0.91, 1.84) | 1.35 (0.97, 1.85) | 0.144 |
Residual platelet reactivity, n (%) | 258 (25.8) | |||
TxB2 (ng/mL)a | 2.7 (0–21) | 2.6 (0–21) | 3.0 (0–15) | 0.102 |
Medication, n (%) | ||||
Statins | 982 (98.3) | 727 (98.2) | 254 (98.4) | 0.825 |
B-blockers | 755 (75.8) | 561 (76.1) | 193 (74.8) | 0.672 |
Calcium channel blockers | 255 (25.6) | 196 (26.5) | 59 (23.0) | 0.272 |
ACE-inhibitors | 263 (26.5) | 200 (27.1) | 63 (24.7) | 0.455 |
ARB | 239 (24.0) | 187 (25.3) | 52 (20.4) | 0.111 |