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Table 3 Univariate (Kaplan-Meier) and multivariate (Cox Regression) analysis for overall survival.

From: Prognostic assessment for patients with cancer and incidental pulmonary embolism

 

N*

OS (95%CI)

p

HR(95%CI)

p

Metastatic/incurable disease

No

45

 

<.001

1

<.001

Yes

188

NR 10.5 (7.3, 13.7)

2.6 (1.5, 4.3)

New Symptoms

No

132

17 (12.7, 21.3)

.029

  

Yes

98

10.1 (5.9, 14.3)

Worsening Symptoms

No

178

15.2 (11.9, 8.4)

   

Yes

49

6.5 (5.2, 7.8)

.013

New or Worsening symptoms

No

111

19 (14.3, 23.8)

.004

1

.002

Yes

121

8.6 (5.3, 11.8)

1.7 (1.2, 2.4)

WCC

<11.3 x109/L

199

14 (9.9, 18.1)

.016

1

 

≥11.3 x109/L

26

5.4 (2.4,8.3)

1.1 (.7, 1.8)

.659

Creatinine

<55μmol/L

29

5.3 (1.5, 9.2)

.021

1

.408

>55μmol/L

195

14 (10, 17.9)

1.2 (.8, 2)

ECOG/WHO PS

  

<.001

 

<.001

0

104

22.9 (17.9, 28.3)

 

1

 

1,2

100

8.8 (6.5, 11)

<.001

1.9 (1.3, 2.8)

.001

3,4

23

3.3 (2.2, 4.4)

<.001

3.7 (2.2, 6.3)

<.001

PESI

  

<.001

 

.081

I,II

28

21 (6.2, 35.7)

 

1

 

III,IV

185

13.8 (10.5, 17.1)

.222

1.5 (.8, 2.5)

.181

V

20

5.5 (4.3, 6.6)

<.001

2.3 (1.1, 4.8)

.026

  1. Numbers are rounded to the first decimal for simplicity were possible. ROC curve analyses were used to identify candidate cut-offs for dichotomisation of continuous variable, indicating WCC 11.3 x109/L and Creatinine 55umol/L as useful cut-offs. 219 complete cases with 152 events available for Cox Regression