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Table 3 Univariate (Kaplan-Meier) and multivariate (Cox Regression) analysis for overall survival.

From: Prognostic assessment for patients with cancer and incidental pulmonary embolism

  N* OS (95%CI) p HR(95%CI) p
Metastatic/incurable disease
No 45   <.001 1 <.001
Yes 188 NR 10.5 (7.3, 13.7) 2.6 (1.5, 4.3)
New Symptoms
No 132 17 (12.7, 21.3) .029   
Yes 98 10.1 (5.9, 14.3)
Worsening Symptoms
No 178 15.2 (11.9, 8.4)    
Yes 49 6.5 (5.2, 7.8) .013
New or Worsening symptoms
No 111 19 (14.3, 23.8) .004 1 .002
Yes 121 8.6 (5.3, 11.8) 1.7 (1.2, 2.4)
WCC
<11.3 x109/L 199 14 (9.9, 18.1) .016 1  
≥11.3 x109/L 26 5.4 (2.4,8.3) 1.1 (.7, 1.8) .659
Creatinine
<55μmol/L 29 5.3 (1.5, 9.2) .021 1 .408
>55μmol/L 195 14 (10, 17.9) 1.2 (.8, 2)
ECOG/WHO PS    <.001   <.001
0 104 22.9 (17.9, 28.3)   1  
1,2 100 8.8 (6.5, 11) <.001 1.9 (1.3, 2.8) .001
3,4 23 3.3 (2.2, 4.4) <.001 3.7 (2.2, 6.3) <.001
PESI    <.001   .081
I,II 28 21 (6.2, 35.7)   1  
III,IV 185 13.8 (10.5, 17.1) .222 1.5 (.8, 2.5) .181
V 20 5.5 (4.3, 6.6) <.001 2.3 (1.1, 4.8) .026
  1. Numbers are rounded to the first decimal for simplicity were possible. ROC curve analyses were used to identify candidate cut-offs for dichotomisation of continuous variable, indicating WCC 11.3 x109/L and Creatinine 55umol/L as useful cut-offs. 219 complete cases with 152 events available for Cox Regression