Skip to main content

Advertisement

Table 2 Correlation of various factors with VASP-PRI

From: Differential impact of diabetes mellitus on antiplatelet effects of prasugrel and clopidogrel

  Prasugrel Clopidogrel
  R
Variable pre 0.5 h 3 h 6 h 20 h pre 0.5 h 3 h 6 h 20 h
Age, yrs −0.28 −0.16 −0.33 −0.31 −0.27 0.14 −0.32 −0.18 −0.30 −0.13
Male −0.29 −0.24 −0.13 −0.04 0.03 0.12 0.28 0.16 0.40 0.28
Body weight, kg 0.01 0.22 0.23 0.29 0.41 0.13 0.27 0.22 0.32 0.16
Body mass index, kg/m2 −0.02 0.23 0.25 0.27 0.38 0.26 0.19 0.13 0.26 0.08
Body surface area, m2 −0.06 0.16 0.21 0.28 0.39 0.14 0.40 0.21 0.37 0.17
Current Smoker −0.02 0.32 0.14 0.26 0.20 0.13 0.31 0.33 0.41 0.41
Alcohol 0.06 −0.06 −0.14 0.10 0.0 0.02 0.36 0.22 0.38 0.1
Hypertension 0.38 0.20 0.28 0.38 0.30 0.46* 0.30 0.16 0.01 0.09
Dyslipidemia 0.02 0.44 0.22 0.50* 0.37 −0.17 −0.23 −0.12 −0.05 −0.11
Diabetes 0.14 0.62** 0.70*** 0.64** 0.68*** −0.20 −0.17 −0.08 −0.12 −0.23
eGFR, ml/min/1.73m2 0.14 0.30 0.39 0.57* 0.44 −0.02 0.19 0.34 0.32 0.37
Platelet counts, ×103/μL 0.43 0.24 0.52* 0.53* 0.39 −0.08 −0.16 −0.10 −0.20 −0.29
Proton pump inhibitor −0.17 0.14 0.07 0.21 0.35 0.06 0.25 0.17 0.27 0.24
Concentration (0.5 h) −0.04 −0.79*** −0.75*** −0.71** −0.83*** 0.09 −0.31 −0.41 −0.57* −0.27
ODI3% 0.15 −0.16 0.18 0.05 0.03 0.12 0.50* 0.48* 0.49* 0.44*
  1. Analysis was performed using the spearman’s correlation coefficient. *P < 0.05; **P < 0.01; ***P < 0.001. ODI = oxygen desaturation index