Differences and similarities between disseminated intravascular coagulation and thrombotic microangiopathy

Thrombosis Journal

Table 2 Diagnostic criteria for TMA [4, 35, 36]

	STEC-HUS	aHUS	TTP	TMA
Hemoglobin (g/dl)	10.0 ≧	10.0 ≧	Hemolysis	10.0 ≧
Platelet (× 10⁴/μl)	15.0 ≧	15.0 ≧	Thrombocytopenia	15.0 ≧
Ogan failure	Renal failure Creatinine ≧1.5 folds of the standard	Renal failure Creatinine ≧1.5 folds of the standard	Neurological symptoms	?
Laboratory finding	Detection of STEC	Genetic abnormality in the complement system	ADAMTS13 < 10%	?

TMA thrombotic microangiopathy, aHUS atypical hemolytic uremic syndrome, TTP thrombotic thrombocytopenic purpura, STEC Shiga toxin-producing Escherichia coli

ISSN: 1477-9560