Table 2 The World Health Organization Quality of Life (WHOQOL-BREF) after 12 months of anticoagulant treatment with warfarin and rivaroxaban in the patients with paroxysmal nocturnal haemoglobinuria
Pt | 1 | Pt | 2 | Pt | 3 | Pt | 4 | All patients (n = 4) | t-test | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
W | R | W | R | W | R | W | R | W | R | p | |
Total (26 items) | 67 | 76 | 42 | 65 | 47 | 58 | 62 | 67 | 54.5 ± 11.9 | 66.5 ± 7.4 | 0.053 |
QOL rate (1 item) | 25 | 75 | 50 | 50 | 25 | 25 | 25 | 75 | 31.3 ± 12.5 | 56.3 ± 23.9 | n. s. |
Satisfaction (1 item) | 50 | 75 | 50 | 25 | 25 | 25 | 50 | 50 | 43.8 ± 12.5 | 43.8 ± 23.9 | n. s. |
Physical (7 items) | 64 | 71 | 29 | 54 | 32 | 50 | 46 | 61 | 42.8 ± 16.0 | 59.0 ± 9.2 | 0.022 |
Psychological (6 items) | 71 | 83 | 50 | 67 | 46 | 58 | 63 | 67 | 57.5 ± 11.6 | 68.8 ± 10.4 | 0.025 |
Social relationships (3 items) | 83 | 83 | 50 | 67 | 92 | 92 | 67 | 75 | 73.0 ± 18.5 | 79.3 ± 10.7 | n. s. |
Environment (8 items) | 69 | 72 | 44 | 81 | 50 | 59 | 78 | 72 | 60.3 ± 15.9 | 71.0 ± 9.1 | n. s. |