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Table 2 The World Health Organization Quality of Life (WHOQOL-BREF) after 12 months of anticoagulant treatment with warfarin and rivaroxaban in the patients with paroxysmal nocturnal haemoglobinuria

From: Antithrombotic therapy with rivaroxaban in five patients with paroxysmal nocturnal haemoglobinuria and thrombotic events

  Pt 1 Pt 2 Pt 3 Pt 4 All patients (n = 4) t-test
W R W R W R W R W R p
Total (26 items) 67 76 42 65 47 58 62 67 54.5 ± 11.9 66.5 ± 7.4 0.053
 QOL rate (1 item) 25 75 50 50 25 25 25 75 31.3 ± 12.5 56.3 ± 23.9 n. s.
 Satisfaction (1 item) 50 75 50 25 25 25 50 50 43.8 ± 12.5 43.8 ± 23.9 n. s.
 Physical (7 items) 64 71 29 54 32 50 46 61 42.8 ± 16.0 59.0 ± 9.2 0.022
 Psychological (6 items) 71 83 50 67 46 58 63 67 57.5 ± 11.6 68.8 ± 10.4 0.025
 Social relationships (3 items) 83 83 50 67 92 92 67 75 73.0 ± 18.5 79.3 ± 10.7 n. s.
 Environment (8 items) 69 72 44 81 50 59 78 72 60.3 ± 15.9 71.0 ± 9.1 n. s.
  1. W Warfarin treatment; R Rivaroxaban treatment. Statistical analysis was performed using Student’s t-test
  2. Significant level was set to p < 0.05. n. s. = not significant