Splanchnic venous thrombosis in JAK2 V617F mutation positive myeloproliferative neoplasms – long term follow-up of a regional case series

Table 1 Patient Demographics

	Budd Chiari		Portal Vein Thrombosis Only		Portal Vein Thrombosis +/− Splenic Vein +/− Superior Mesenteric Vein
Number	3		7		4
Sex	Male	0	Male	3	Male	0
Sex	Female	3	Female	4	Female	4
Age	Mean	38.6	Mean	47.5	Mean	53.5
Age	Range	22–49	Range	36–67	Range	38–84
Type of MPN
PV	1		2		2
ET	2		1		0
PMF	0		0		0
Latent/Unclassifiable	0		4		2
Blood Counts
Hb (g/l)	Mean	136	Mean	133^a	Mean	140
Hb (g/l)	Range	127-145	Range	93–200	Range	111–179
White Cell Count (× 10⁹/l)	Mean	16.6	Mean	9.4^a	Mean	11.6
White Cell Count (× 10⁹/l)	Range	11.7–21.3	Range	5.1–14	Range	8.3–17
Platelets (×10⁹/l)	Mean	592	Mean	358^a	Mean	537
Platelets (×10⁹/l)	Range	539-656	Range	283–649	Range	369–861
Haematocrit	Mean	0.62^a	Mean	0.40^a	Mean	0.41
Haematocrit	Range	0.39–0.46	Range	0.31–0.57	Range	0.33–0.54
Other Inherited pro-thrombotic condition	0		0		0
On Anticoagulant at time event	1		0		0
On Anti-platelet at time of event	0		0		0
Other cardiovascular risk factors	0		1		0
On OCP/HRT at time of event	1		0		0
Previous Venous Thrombosis	1		1		0
Previous Arterial Thrombosis	0		0		0
Prior features suggestive MPN	1		3		0
Liver Intervention
Initial TIPPS	2		0		0
Liver Transplant	2		0		0
Failed Transplant	1		0		0
Complications
Ascites	3		1		2
Splenomegaly	2		5		3
Varices	0		6		2
Follow-up (months)	Mean	114	Mean	116	Mean	50.7
Follow-up (months)	Range	47–211	Range	65–204	Range	8–118

This shows the demographics of the patient population in each subclassification of splanchnic vein thrombosis
^aData not available for 1 patient

ISSN: 1477-9560