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Table 1 TTP-like patient demographics, laboratory test results and treatment

From: Thrombotic thrombocytopenic purpura (TTP)-like syndrome in the HIV era

 

Age

Sex

Hb

WCC

Plts

RDW

Fragments

INR

PTT

D-dimers

DATT

LDH

Haptoglobin

Urea

Creatinine

HIV-infected

HIV VL

CD4+ T cell count

ARV therapy

Days of PE

Units

Yrs

 

g/dL

×109/L

×109/L

%

  

s

mg/L

  

g/L

mmol/L

ug/L

 

copies/mL

Cells/ul

  

Reference range

  

11,6 16,4

3,9 12,60

186–454

12,4 17,3

Absent

 

31–48

< 0.25

Negative

100–190

0,4-2,4

2.1–7.1

49–90

  

332–1642

  

1

48

M

8.8 (11.5)

10.4

33 (276)

33.8

3+

1.02

ND

1.48

ND

2365 (300)

< 0.1

9.9

126

Yes

LTDL

141

Yes

20

2

37

F

10.5 (12.4)

12.85

18 (351)

19.6

2+

1.81

32.6

ND

Neg

1073 (320)

< 0.1

12.4

105

Yes

LTDL

346

Yes

20

3

39

M

7.1 (12.9)

5.42

12 (268)

24.5

2+

1.09

32.6

ND

Neg

698 (468)

< 0.1

4

88

Yes

321,158

194

Yes

10

4

47

F

7.2 (12.8)

7.84

8 (219)

23.3

3+

1.14

30.8

3.20

ND

2023 (311)

< 0.1

9

128

Yes

191,000

134

No

25

5

32

F

4.6 (11.5)

8.56

8 (272)

30.5

3+

1.12

32.9

1.16

ND

941 (191)

< 0.1

1.8

57

Yes

373,000

80

No

11

6

27

F

8 (14.1)

4.92

35 (244)

32.6

3+

1.01

ND

11.90

Negative

2102 (180)

< 0.1

4.7

52

Yes

8642

182

Yes

10

7

43

F

10.2 (12.8)

8.4

16 (86)

24.6

3+

1.01

30.0

0.75

IgG +

2005 (160)

< 0.1

9.1

79

No

N/A

N/A

N/A

12

8

30

F

7.3 (9.7)

6.56

15 (175)

33.9

3+

1.15

ND

11.90

Negative

1836 (178)

ND

4.8

60

Yes

42

113

Yes

10

9

35

F

5.5 (11.1)

9.17

5 (280)

26.6

3+

1.2

31.0

6.49

Negative

1768 (182)

< 0.1

3.8

71

Yes

ND

585

Yes

18

10

45

F

6.7 (10.4)

4.16

18 (105)

22.7

3+

1.06

44.3

ND

IgG +

950 (227)

< 0.1

4.1

67

Yes

228,912

54

No

20

11

43

F

7.8 (9.5)

10.4

18 (23)

23.9

1+

1.62

43.1

0.56

IgG +

1441

ND

17

211

No

N/A

N/A

N/A

12b

12

44

F

6.3 (14.3)

13.91

3 (290)

27.9

3+

1.21

43.1

10.00

ND

2708 (478)

< 0.1

7.8

113

Yes

2150

187

Yes

18

13

43

F

6.1 (10.4)

10.5

10 (274)

25

3+

1.17

36.9

7.13

ND

1357 [32]

< 0.1

5.5

94

Yes

72,905

264

No

12

14

40

M

7.4 (10.8)

4.15

21 (254)

20.6

2+

1.11

41.1

1.0

IgG +

1068 (273)

< 0.1

7.7

101

Yes

26,065

215

No

14

15

34

F

6.5 (10.7)

8.96

6 (270)

19

2+

1.35

33.8

17.00

Negative

1683 (257)

< 0.1

6.4

96

No

N/A

N/A

N/A

12

16

56

F

5.8 (8.5)

14.7

5 (328)

34.2

3+

1.3

33.5

ND

Negative

3339 (305)

< 0.1

6.6

80

Yes

LTDL

180

Yes

11

17

34

F

6.7 (12.5)

13.67

5 (248)

27.2

3+

1.28

31.7

0.00

IgG +

2404 (206)

< 0.1

6.5

110

Yes

562,635

421

No

11

18

44

M

7.5

19.35

25

20.2

3+

1.14

34.0

ND

ND

5472

ND

27.3

262

Unknown

ND

ND

Unknown

1a

19

33

F

6.5 (10.2)

8.9

6 (203)

19

2+

1.35

33.8

17.00

Negative

1683 (195)

< 0.1

6.4

96

No

N/A

NA

N/A

12

20

38

F

7.9 (9.5)

5.6

3 (253)

15.2

2+

1.05

43.6

1.93

IgG +

827 (244)

< 0.1

5.3

67

Yes

2,030,000

100

No

15

21

35

M

2.7 (7)

13.2

29 (134)

13.5

1+

2.38

92.3

0.97

IgG+

978 (476)

< 0.1

5.6

136

Yes

1,010,000

34

No

15

Median

39

 

7.1 (10.95)

9.065

12 (253.5)

24.5

 

1.14

33.6

2.565

 

1683 (244)

 

6.6

96

 

209,956

181

 

12

IQR (25–75%)

34–44

 

6,35-7725

6,56-13,2

 

20,2

27,725

6–20,3

1.08–1.2

32–43

0.99–10.5

 

1069-2299

 

1.2–3

73–122.7

 

21,709-420,409

110–227

 

11–18

  1. aPatient demised on day 1. b Patient defaulted after 12 days of plasma exchange. Values in brackets denote discharge haemoglobin, platelet and LDH levels
  2. Abbreviations: Yrs years, Hb haemoglobin, WCC White cell count, RDW red cell distribution width, Plts platelets, LDH lactate dehydrogenase, ARV antiretroviral therapy, VL viral load, LTDL viral load lower than detectable limit
  3. PE:plasma exchange, N/A not applicable
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Thrombosis Journal

ISSN: 1477-9560

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