Circulating histone H3 levels in septic patients are associated with coagulopathy, multiple organ failure, and death: a single-center observational study

Table 1 Basic characteristics of the study patients

	All	Survivors (n = 73)	Non-survivors (n = 12)	p
Age	71 (24–92)	71 (n = 73)	72.5 (n = 12)	0.64
APACHE II	19 (7–33)	18.5 (n = 72)	22 (n = 12)	0.09
SOFA score	8 (3–17)	7 (n = 68)	11 (n = 11)	< 0.01
SIRS score	3 (0–4)	3 (n = 72)	3 (n = 12)	0.72
DIC score	4 (1–8)	4 (n = 65)	6 (n = 12)	0.06
Shock (%)	47.1	42.5	75	0.06

APACHE II Acute Physiology and Chronic Health Evaluation II without the Glasgow Coma Scale component, SOFA Sequential Organ Failure Assessment without the Glasgow Coma Scale component, SIRS Systemic Inflammatory Response Syndrome, DIC Disseminated Intravascular Coagulation;
Data for all subjects are shown as median (minimum–maximum), and data for survivors and non-survivors are shown as median (number of patients analyzed)
Differences between survivors and non-survivors were analyzed by the Mann–Whitney U test, except for shock (%), which was analyzed by the chi-square test

ISSN: 1477-9560