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Table 3 PAR3 cleaving proteases

From: Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases

  Protease Major cleavage site Additional cleavage sites
Mammalian proteases Thrombin K38T39 mouse PAR3 at K37S38
aPC R41G42  
FXa R41G42  
Trypsin unknown