Thrombosis Journal

Table 3 PAR3 cleaving proteases

From: Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases

	Protease	Major cleavage site	Additional cleavage sites
Mammalian proteases	Thrombin	K³⁸T³⁹	mouse PAR3 at K³⁷S³⁸
	aPC	R⁴¹G⁴²
	FXa	R⁴¹G⁴²
	Trypsin	unknown

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ISSN: 1477-9560

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