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Table 2 Parameters of APTT waveform in patients with and without DIC and healthy volunteers

From: Usefulness of the APTT waveform for the diagnosis of DIC and prediction of the outcome or bleeding risk

   HV Without DIC Pre-DIC DIC Without HF With HF
2ndDP Time (seconds) 35.5***
(32.6–37.4)
43.9
(36.6–52.7)
54.6*
(41.0–71.3)
63.7***
(47.4–84.9)
58.8***
(46.2–73.9)
72.5***
(49.7–110)
Height (mabs) 457**
(411–535)
648
(379–973))
460*
(191–772)
151***
(83.2–326)
286***
(144–427)
107***
(26.5–148)
NH (mabs) 234**
(170–255)
316
(164–499)
176**
(93.2–308)
66.4***
(39.4–150)
134***
(61.6–188)
55.0***
(14.5–64.5)
Width (sec) 7.45***
(6.80–8.00)
12.9
(11.2–16.8)
17.7**
(12.5–24.3)
15.1*
(12.4–20.5)
15.1*
(12.4–20.5)
21.4***
(12.7–38.2)
1stDP Time (sec) 38.7***
(36.3–40.8)
50.2
(41.2–58.6)
60.5*
(45.8–76.4)
70.7***
(52.1–96.8)
64.9***
(52.2–81.0)
78.6***
(51.8–128.2)
Height (mabs) 183***
(144–200))
389
(241–544)
251**
(154–358)
103***
(64.2–208)
200***
(116–257)
61.2***
(36.8–93.9)
Width (sec) 19.5***
(18.0–20.3)
65,2
(54.8–72.1)
65.2
(54.0–195)
66.5
(56.0–200)
64.6
(57.6–200)
75.1
(55.0–200)
1/2FFP Time (sec) 40.9***
(37.8–42.7)
52.5
(43.1–61.5)
61.6*
(47.1–78.9)
75.0***
(54.8–99.3)
69.1***
(54.8–87.9)
80.9***
(54.7–142)
Height (mabs) 242***
(207–305)
462
(338–586)
328*
(271–490)
265***
(178–371)
319***
(240–399)
195***
(170–286)
  1. 2ndDP, second derivative peak; 1stDP, first derivative peak, 1/2FFP, fibrin formation peak; NH, negative height; DIC, disseminated intravascular coagulation; HF, hypofibrinogenemia
  2. Data was shown as median (25–75%tile)
  3. ***, p < 0.001, **, p < 0.01 or: *p < 0.05 compared with patients without DIC